Successful treatment of multi-resistant Stenotrophomonas maltophilia meningitis with ciprofloxacin in a pre-term infant

Lo, Wen-Tsung; Wang, Chih‐Chien; Lee, Chuen-Ming; Chu, Mong-Ling

doi:10.1007/s00431-002-1095-5

Cited by 32 publications

(30 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…5 Two cases of late onset sepsis with meningitis were treated successfully with ciprofloxacin alone or in combination with cotrimoxazole. 6,7 Mother had no history of fever, UTI or prolonged rupture of membranes. Maternal swab, blood culture, and sampling of environmental sources were not done.…”

Section: Discussionmentioning

confidence: 99%

Early onset sepsis with pneumonia in a full term neonate due to Stenotrophomonas maltophilia

Basany

Aepala

2015

Int J Contemp Pediatr

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Early onset sepsis with pneumonia in a full term neonate due to Stenotrophomonas maltophilia

Basany

Aepala

2015

Int J Contemp Pediatr

View full text Add to dashboard Cite

“…The fluoroquinolones (especially ciprofloxacin) have been used successfully in some patients with meningitis due to gram-negative organisms [105][106][107][108][109]. However, on the basis of limited published literature, these agents should only be utilized for meningitis caused by multidrugresistant gram-negative bacilli, or when patients have not responded to or cannot receive standard antimicrobial therapy (A-III).…”

Section: Once the Bacterial Etiology Of Meningitis Is Established Whmentioning

confidence: 99%

Pneumococcal Meningitis Successfully Treated with Adjuvant Management of Intrathecal Vancomycin, Oral Rifampicin and Shunt Surgery

Yim

Kim

2016

J Neurocrit Care

View full text Add to dashboard Cite

OBJECTIVESThe objective of these practice guidelines is to provide clinicians with recommendations for the diagnosis and treatment of bacterial meningitis. Patients with bacterial meningitis are usually treated by primary care and emergency medicine physicians at the time of initial presentation, often in consultation with infectious diseases specialists, neurologists, and neurosurgeons. In contrast to many other infectious diseases, the antimicrobial therapy for bacterial meningitis is not always based on randomized, prospective, double-blind clinical trials, but rather on data initially obtained from experimental animal models of infections. A model commonly utilized is the experimental rabbit model, in which animals are anesthetized and placed in a stereotactic frame. In this procedure, the cisterna magna can be punctured for frequent sampling of CSF and injection of microorganisms. Frequent sampling of CSF permits measurement of leukocytes and chemical parameters and quantitation of the relative penetration of antimicrobial agents into CSF and the effects of meningitis on this entry parameter, the relative bactericidal efficacy (defined as the rate of bacterial eradication) within purulent CSF, and CSF pharmacodynamics. Results obtained from these and other animal models have led to clinical trials of specific agents in patients with bacterial meningitis.

show abstract

“…This bacterium is usually not susceptible to commonly used antibacterial agents [2]. Infection by highly resistant Stenotrophomonas maltophilia is known to cause severe infection, septic shock and meningitis with a high mortality rate, especially in severely ill patients [3]. However, treating these bacteria with effective antibiotics is associated with a better outcome [1].…”

mentioning

confidence: 99%

“…However, treating these bacteria with effective antibiotics is associated with a better outcome [1]. Although the use of ciprofloxacin in treating Stenotrophomonas maltophilia is frequently reported [3], its use in the neonatal age group is still not universally accepted. Animal studies showed concerns regarding the side effect chondrotoxicity.…”

mentioning

confidence: 99%

Treatment of Stenotrophomonas neonatal urinary tract infection with instillation of ciprofloxacin

Khassawneh

Hayajneh

2010

Pediatr Nephrol

View full text Add to dashboard Cite

Successful treatment of multi-resistant Stenotrophomonas maltophilia meningitis with ciprofloxacin in a pre-term infant

Cited by 32 publications

References 8 publications

Early onset sepsis with pneumonia in a full term neonate due to Stenotrophomonas maltophilia

Early onset sepsis with pneumonia in a full term neonate due to Stenotrophomonas maltophilia

Pneumococcal Meningitis Successfully Treated with Adjuvant Management of Intrathecal Vancomycin, Oral Rifampicin and Shunt Surgery

Treatment of Stenotrophomonas neonatal urinary tract infection with instillation of ciprofloxacin

Contact Info

Product

Resources

About