Abstract:Elli beş yaşında 85 kg olan erkek hasta mantar yedikten 18 saat sonra bulantı, kusma, ishal ve halsizlik şikayeti ile ÖZ Yüz kadarının toksik olduğu bilinmekle beraber, yeryüzünde 5.000'den fazla mantar çeşidi bulunmaktadır. Bunların arasında en zehirli türler Amanita ve Gallerina türlerine ait olanlardır. Türkiye'deki ölümcül mantar zehirlenmelerinin %90'ından sorumlu olan, ciddi karaciğer, böbrek ve santral sinir sistemi hasarı ile seyreden alfa-amanitin ve beta-amanitin toksinleri Amanita phalloides tarafın… Show more
Recent developments in chemistry, biosynthesis, analytical methods, and transformations of flavonolignans from silymarin are presented. Their pharmacology, biological activities, SAR and safety with special attention to the chirality are discussed.
Recent developments in chemistry, biosynthesis, analytical methods, and transformations of flavonolignans from silymarin are presented. Their pharmacology, biological activities, SAR and safety with special attention to the chirality are discussed.
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