Successful Treatment of Olecranon Bursitis Caused byTrueperella bernardiae: Importance of Environmental Exposure and Pathogen Identification

Abstract

A livestock farmer with a history of arthropathy presented with unilateral olecranon bursal swelling and tenderness. Multiple wound and intraoperative cultures revealed growth of Trueperella bernardiae, a Gram-positive coccobacillus, with symptom resolution following appropriate antimicrobial therapy. To our knowledge, this is the first case report of olecranon bursitis caused by this organism. Coryneform bacteria are often regarded as contaminants in clinical cultures, but advanced techniques for species identification may reveal expanded pathogenic potential of individual species like T. bernardiae and elucidate epidemiologic clues for osteoarticular infections in these cases.

Trueperella bernardiae bloodstream infection following onco-gynaecologic surgery and literature review

“…We conducted a literature search in Pubmed, with the keywords "Trueperella bernardiae" OR "Arcanobacterium bernardiae", which resulted in 27 articles. The more relevant articles were analyzed and epidemiological and clinical features of all recently diagnosed cases of T. bernardiae were provided in the Table 1 [6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23]. We highlight that T. bernardiae infection has been mostly identified in immunocompromised hosts, with no apparent age or gender predilection, often diagnosed in polymicrobial cultures, and presenting a good prognosis.…”

“…We highlight that T. bernardiae infection has been mostly identified in immunocompromised hosts, with no apparent age or gender predilection, often diagnosed in polymicrobial cultures, and presenting a good prognosis. T. bernardiae was deemed to cause skin and soft tissue including two cases of breast abscess, osteoarticular, BSIs with severe complications, and two cases of brain abscess following otitis media are also reported [6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23]. Of note, among soft tissue and osteoarticular infections, there are various cases related with arthroplasty and, as in our case, surgical wound.…”

“…Trueperella bernardiae is a commensal of the human skin and oropharynx, coryneform, facultative anaerobic, catalase and oxidase negative, Gram-positive bacillus [4]. Despite human infections with Trueperella spp hav-ing a low prevalence, the addition to the Matrixassisted laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry database of the main spectrum for T. bernardiae made its pathogenicity increasingly documented in literature [5][6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23]. We report a case of T. bernardiae bloodstream infection (BSI) following onco-gynaecologic surgery together with a comprehensive literature review of T. bernardiae infections to help clinicians be aware about epidemiological, clinical, and microbiologic features of this emerging pathogen.…”

A Case Report of Trueperella bernardiae Pelvic Osteomyelitis and Sepsis: Literature Review of Trueperella bernardiae Infections

“…However, the literature has also reported the isolation of T. bernardiae in porcine stool [3]. One case report also mentions T. bernardiae infection after significant pig exposure [4]. Interestingly, it has not been considered pathogenic until recently, primarily because of initially being classified as coryneform bacteria, which led to its identification as non-pathogenic commensal.…”

Identification of Trueperella bernardiae isolated from peking ducks (Anas platyrhynchos domesticus) by phenotypical and genotypical investigations and by a newly developed loop-mediated isothermal amplification (LAMP) assay

“…In humans, T. bernardiae was first described as an opportunistic pathogen and later could be identified alone or in combination with other bacteria as causing joint infections (Gilarranz et al 2016;Gowe et al 2018), urinary tract infections (Lepargneur et al 1998), abscesses (Parha et al 2015;VanGorder et al 2016;Calatrava et al 2019;Pan et al 2019), wound infections (Weitzel et al 2011;Rattes et al 2016;Cobo et al 2017), a diabetic foot infection (Schneider et al 2015), bacteremia (Otto et al 2013;Roh et al 2019), and septic thrombophlebitis (Lawrence et al 2018).…”