Successful Treatment of Persistent Macular Holes Using “Heavy Silicone Oil” as Intraocular Tamponade

Rizzo, Stanislao; Belting, Claudia; Genovesi-Ebert, Federica; Cresti, Federica; Vento, Andrea; Martini, Riccardo

doi:10.1097/01.iae.0000250006.76155.3d

Cited by 57 publications

(56 citation statements)

References 15 publications

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“…It has been used in several clinical series for the treatment of complicated RRD and recurrent macular hole. 20,27,32,35,49,50 The substance was removed on average after 2 months and complication rates seem to be significantly lower compared to F6H8 or other earlier tamponades. However, significant rates of emulsification and a rise in IOP could still be noticed.…”

Section: Heavy Silicone Oilsmentioning

confidence: 99%

“…[20][21][22]27,32,33 Another subgroup is myopic patients with RRD associated with a macular hole, a posterior staphyloma, or recurrent macular holes. 11,12,21,26,34,35,50 Uncommon indications that were included into clinical trials as single cases only were tractional RD associated with diabetic retinopathy, 6,11,14,15 hypotony, 11 and retinal necrosis. 6 Few patients with breaks in the superior periphery in addition to inferior pathology have been treated with heavy tamponades.…”

Section: Indicationsmentioning

confidence: 99%

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Heavy tamponade 1: a review of indications, use, and complications

Heimann

Stappler

Wong

2008

Eye

117

125

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Background Heavier than water intraocular tamponades have several theoretical advantages over conventional tamponades, especially in the treatment of complicated retinal detachments and proliferative viteroretinopathy of the lower fundus periphery. However, initial clinical series of various heavy tamponades have reported significant complication rates. Therefore, heavy tamponades have not found widespread acceptance. Three recently developed heavy silicone oil tamponades, Oxane HD, Densiron 68, and HWS 46-3000, are much better tolerated and presently seem to enter routine clinical practice. Materials and methods Literature review of 21 publications on the clinical application of 9 different heavy tamponades (fluorosilicone, C10F18, F6H8, OL62HV, Oxane HD, O62, F6H8-silicone oil mixture, Densiron 68, and HWS 46-3000). Results The first generation (fluorinated silicone and perfluorocarbon liquids) and second generation (partially fluorinated alkanes) of heavy tamponades were associated with relatively high complication rates, for example, tamponade emulsification, intraocular inflammation, and rise in intraocular pressure. The complication spectrum of the new generation of heavy silicone oils (Oxane HD, Densiron 68, and HWS 46-3000) seems to be comparable to conventional silicone oil tamponades while providing better support for the inferior retina and the posterior pole. Conclusion The recently developed heavy silicone oil tamponades are safe and effective tools for the use of complicated retinal detachments of the inferior fundus.

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Section: Heavy Silicone Oilsmentioning

confidence: 99%

Section: Indicationsmentioning

confidence: 99%

Heavy tamponade 1: a review of indications, use, and complications

Heimann

Stappler

Wong

2008

Eye

117

125

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“…Rizzo et al achived success of reoperation using "heavy silicon oil" (ref. 10 ). This type of tamponade was effective even in the upright position.…”

Section: Discussionmentioning

confidence: 99%

Re-operation of idiopathic macular hole after failed initial surgery

Hejsek¹,

Dusová²,

Stepanov³

et al. 2014

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub

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Background. Persistent idiopathic macular hole (IMH) after initial pars plana vitrectomy (PPV) appears in approx. 12% of cases. It is, therefore, one of the most common complications. IMH re-operation results tend to be better in eyes where IMH had been closed, while IMH re-operations in cases when the initial surgery had failed tend to be less successful: IMH often becomes even larger and visual acuity decreases, anatomical success rate of closure is about 60% and the resulting postoperative visual acuity is about 20/100. Aims. To establish anatomical and functional success rate of repeated operations of recurrent idiopathic macular hole. Materials and Methods. We evaluated the retrospective results of re-operations of persisting IMH that is cases in which the initial surgery did not result in closure: 6 eyes in 6 patients out of the overall 55 operated on IMH (primary PPV failed in almost 11% of cases). The follow-up period was 18 months (since the first surgery). Results and Conclusion. After the second PPV, the IMH was closed in 100% of operated eyes. It was not necessary to perform a third PPV during the follow-up period. In all cases the visual acuity improved. Anatomical and functional results of IMH treatment can be considered satisfactory. We consider the following combination of factors significant for the anatomical success rate of PPV: IMH size and stage, technical precision of the ILM peeling and the suction of the IMH contents, strict adherence to the recommended head positioning in early postoperative period, and IMH duration.

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“…In both patients, the macular hole closed and visual acuity improved from 20/200 to 20/40 and from 20/600 to 20/100. No complications were reported [89]. Lappas et al [90] treated 12 patients with macular hole persisting after the standard procedure.…”

Section: Endotamponades Heavier Than Watermentioning

confidence: 99%

“…Jonas and Jager [88] used F 6 H 8 for the retreatment of a patient with persistent macular hole, but had significant complication after 4 weeks (epiretinal membrane on the surface of the complete retina and emulsification); however, the macular hole was closed and visual acuity increased from 20/200 to 20/60. Rizzo et al [89] reported on 2 cases that were treated with vitrectomy, repeat ILM peeling and heavy endotamponade (Oxane HD) for recurrent macular hole after the standard procedure. In both patients, the macular hole closed and visual acuity improved from 20/200 to 20/40 and from 20/600 to 20/100.…”

Section: Endotamponades Heavier Than Watermentioning

confidence: 99%

Long-Lasting Endotamponades in Vitreoretinal Surgery

Wagenfeld

Zeitz²,

Skevas³

et al. 2010

Ophthalmologica

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In modern vitreoretinal surgery, a variety of long-lasting endotamponades is available. These endotamponades differ in physical and chemical properties and their usage is based on certain pathological and surgical considerations. With modern endotamponades the treatment and prognosis for some severe diseases of the posterior segment was improved. Besides these supportive features of new endotamponades, the surgeon has to keep in mind that certain steps, like a complete removal of the vitreous and of any traction, are crucial for the success of an operation and that the most supportive step for the retina is complete endotamponade. This review gives an overview of longlasting endotampoandes in vitreoretinal surgery and of the indications for their usage.

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Successful Treatment of Persistent Macular Holes Using “Heavy Silicone Oil” as Intraocular Tamponade

Abstract: HSO can be a useful tool in the treatment of persistent macular hole. OCT images showed that the tamponade was effective in the upright position in the foveal region. OCT allowed determination of the time of tamponade removal according to the anatomical stage of hole closure.

Cited by 57 publications

References 15 publications

Heavy tamponade 1: a review of indications, use, and complications

Heavy tamponade 1: a review of indications, use, and complications

Re-operation of idiopathic macular hole after failed initial surgery

Long-Lasting Endotamponades in Vitreoretinal Surgery

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