Successful Treatment Response with Aripiprazole Augmentation of SSRIs in Refractory Obsessive–Compulsive Disorder in Childhood

Ardıç, Ülkü Akyol; Ercan, Eyüp Sabri; Kutlu, Ayşe; Yüce, Deniz; İpçi̇, Melis; İnci̇, Sevim Berrin

doi:10.1007/s10578-016-0694-8

Cited by 17 publications

(5 citation statements)

References 34 publications

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“…22 For treatment-refractory OCD, open-label trials and case studies have shown that augmentation of SSRIs with risperidone or aripiprazole can reduce OCD symptoms in children. [28][29][30] Table 1.…”

Section: What Types Of Interventions or Treatments Can Results In Cli...mentioning

confidence: 99%

Diagnosing and Treating Pediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcal Infections

O’Dor,

Kuhn,

Williams

et al. 2024

Prim. Care Companion CNS Disord.

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The Psychiatric Consultation Service at Massachusetts General Hospital sees medical and surgical inpatients with comorbid psychiatric symptoms and conditions. During their twiceweekly rounds, Dr Stern and other members of the Consultation Service discuss diagnosis and management of hospitalized patients with complex medical or surgical problems who also demonstrate psychiatric symptoms or conditions. These discussions have given rise to rounds reports that will prove useful for clinicians practicing at the interface of medicine and psychiatry.

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Section: What Types Of Interventions or Treatments Can Results In Cli...mentioning

confidence: 99%

Diagnosing and Treating Pediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcal Infections

O’Dor,

Kuhn,

Williams

et al. 2024

Prim. Care Companion CNS Disord.

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“…Previous studies showed that aripiprazole was effective as a monotherapy in children, aged between 10-12 years old (Ercan et al, 2015; O’Connor et al, 2005; Akyol Ardic et al, 2017). In the present study, all of the children had high scores at baseline CY-BOCS evaluations, and most of them had at least one comorbid psychiatric disorder.…”

Section: Discussionmentioning

confidence: 99%

Treatment of preschool children with obsessive compulsive disorder

Izmir

Ercan

2022

Clin Child Psychol Psychiatry

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The aim was to examine the clinical features of Obsessive-Compulsive Disorder (OCD) in preschool and the effectiveness of aripiprazole with a standardized Cognitive-Behavioral Family Therapy (CBFT) in the treatment of preschoolers with OCD. Twelve preschool children, 36–72 months of age were diagnosed with OCD according to the Diagnostic and Statistical Manual of Mental Disorders, the Fifth Edition criteria by a fellowship-trained child and adolescent psychiatrist. They were evaluated with Kiddie Schedule for Affective Disorders and Schizophrenia for School-Age Children Present and Lifetime version and Childhood Yale-Brown Obsessive Compulsive Scale (CY-BOCS) at baseline, at the end of the 12th and 24th weeks of treatment. The baseline mean of total CY-BOCS score decreased from 33.67 to 13.83 at the 12th week and 5.58 at the end of the 24th week of treatment. Also, 66.7% of them had at least one psychiatric comorbidity. Overall, this study revealed the effect of aripiprazole with CBFT in preschool-aged children with OCD. Also, the presence of comorbidity that is seen frequently in preschoolers with OCD may complicate the treatment. Therefore, there is a need to increase awareness of OCD and its comorbidities in preschoolers to supply treatment at an early age.

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“…Treatment of anxiety with SSRIs is wellknown. Some studies showed the beneficial results of augmentation of therapeutic effect of SSRIs by adding an aripiprazole in the treatment of obsessive compulsive disease (OCD) and depression (Akyol-Ardic et al, 2016;Sugawara, Sakamoto, Harada, Shimizu, & Ishigooka, 2016). Also aripiprazole monotherapy effective in the treatment of OCD (Connor, Payne, Gadde, Zhang, & Davidson, 2005).…”

Section: Discussionmentioning

confidence: 99%

Effectiviness of Low Dose Aripiprazole in the Treatment of Austistic Child With Separation Anxiety Disorder

Uzun¹,

Akça²

2017

JPR

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Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder that begins in childhood, causes significant problems in communication and significantly affects daily functioning and quality of life of the individual. Many psychiatric disorders, such as anxiety disorders, ticdisorders, and attention deficit hyperactivity disorder may be comorbid with ASD. Atypical antipsychotics are frequently using the treatment of irritability and comorbid psychiatric disorders in individuals with ASD. Aripiprazole popularity has raised in recent years due to its efficacy profile. Effectiveness of low dose aripiprazole as monotherapy in the treatment of psychiatric disorders are remarkable. In this case report, we will present effectiveness of low dose aripiprazole monotherapy in the treatment of an autistic child with separation anxiety disorder and Tourette Syndrome.

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Successful Treatment Response with Aripiprazole Augmentation of SSRIs in Refractory Obsessive–Compulsive Disorder in Childhood

Cited by 17 publications

References 34 publications

Diagnosing and Treating Pediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcal Infections

Diagnosing and Treating Pediatric Autoimmune Neuropsychiatric Disorder Associated With Streptococcal Infections

Treatment of preschool children with obsessive compulsive disorder

Effectiviness of Low Dose Aripiprazole in the Treatment of Austistic Child With Separation Anxiety Disorder

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