This paper is concerned with experimental investigation of the linear opening-pressure drop ( −Δ ) relationship of new valve core in managed pressure drilling (MPD). Based on the linear − Δ relationship in theoretical results, the actual − Δ relationships are obtained by testing the flow rate, displacement of the valve core, and pressures at the import and export. Under all three working conditions, the theoretical −Δ relationship almost agrees with the experimental result, and the accuracy of the theoretical design is validated. In addition, the flow coefficient ( V ) is also tested in the experimental process to judge the throttling characteristics of the new valve core and the proper working conditions.