Succession of oral bacterial colonizers on dental implant materials: An in vitro biofilm model

Siddiqui, Danyal A.; Fidai, Alikhan B.; Natarajan, Smriti G.; Rodrigues, Danieli C.

doi:10.1016/j.dental.2021.12.021

Cited by 13 publications

(9 citation statements)

References 82 publications

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“…In a study of 46 young people, they found that this bacterium is a colonizer on implants in young patients [39] . Veillonella parvula together with Fusobacterium nucleatum colonize implants on the first day of placement [40] . This bacterium has adherence to sterile titanium, hydroxyapatite and zirconium implants [41] .…”

Section: Colonization Of Dental Implantsmentioning

confidence: 99%

Veillonella parvula: An update from a stomatological point of view

García¹,

Martínez²,

Ramos³

et al. 2022

Int. J. Appl. Dent. Sci.

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Introduction: Veillonella species found in oral cavity are among the most abundant members of the oral flora, they are involved in bone and joint infections. Objective: To analyze the literature on V. parvula, particularly bacteremia, treatment, colonization of dental implants, and symbiosis with other microorganisms. Methodology: A review of the literature was carried out in the databases PubMed, Google Scholar and SCOPUS with the words ¨Veillonella parvula and Treatment and Clinical Advancements and biological markers, and dental implants". Results: Veillonella parvula has different clinical manifestations and usually presents in a variety of systemic diseases. Among its treatment is the use of antibiotics, surgical lavage and photodynamic therapy. This bacterium is a very effective colonizer of dental implants of different composition. It is related to several oral microorganisms, including Streptococcus, Fusobacterium nucleatum and Aggregatibacter actinomycetemcomitans. Conclusion:It is important to identify V. parvula for proper treatment, as it exacerbates various oral diseases by making symbiosis with other oral pathogens.

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Section: Colonization Of Dental Implantsmentioning

confidence: 99%

Veillonella parvula: An update from a stomatological point of view

García¹,

Martínez²,

Ramos³

et al. 2022

Int. J. Appl. Dent. Sci.

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“…However, oral bacteria from dental tissue inflammatory sites can adhere to any surface of materials placed in the oral cavity, including titanium. As a result, bacterial biofilm formation on titanium remains a significant clinical challenge, leading to peri-implantitis and the failure of dental implantation ( Daubert and Weinstein, 2019 ; Dhaliwal et al, 2021 ; Siddiqui et al, 2022 ). When exposed to fermentable carbohydrates, acid-producing bacteria within biofilms, such as Streptococcus mutans , can generate a low pH microenvironment via bacterial metabolism, and electrochemical circuits via a potential difference ( Pitts et al, 2017 ; Yu et al, 2022 ).…”

Section: Introductionmentioning

confidence: 99%

Antibiofilm peptides enhance the corrosion resistance of titanium in the presence of Streptococcus mutans

Wang,

Yue,

Liu

et al. 2024

Front. Bioeng. Biotechnol.

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Titanium alloys have gained popularity in implant dentistry for the restoration of missing teeth and related hard tissues because of their biocompatibility and enhanced strength. However, titanium corrosion and infection caused by microbial biofilms remains a significant clinical challenge leading to implant failure. This study aimed to evaluate the effectiveness of antibiofilm peptides 1018 and DJK-5 on the corrosion resistance of titanium in the presence of Streptococcus mutans. Commercially pure titanium disks were prepared and used to form biofilms. The disks were randomly assigned to different treatment groups (exposed to S. mutans supplied with sucrose) including a positive control with untreated biofilms, peptides 1018 or DJK-5 at concentrations of 5 μg/mL or 10 μg/mL, and a negative control with no S. mutans. Dynamic biofilm growth and pH variation of all disks were measured after one or two treatment periods of 48 h. After incubation, the dead bacterial proportion, surface morphology, and electrochemical behaviors of the disks were determined. The results showed that peptides 1018 and DJK-5 exhibited significantly higher dead bacterial proportions than the positive control group in a concentration dependent manner (p < 0.01), as well as far less defects in microstructure. DJK-5 at 10 μg/mL killed 84.82% of biofilms and inhibited biofilm growth, preventing acidification due to S. mutans and maintaining a neutral pH. Potential polarization and electrochemical impedance spectroscopy data revealed that both peptides significantly reduced the corrosion and passive currents on titanium compared to titanium surfaces with untreated biofilms, and increased the resistance of the passive film (p < 0.05), with 10 μg/mL of DJK-5 achieving the greatest effect. These findings demonstrated that antibiofilm peptides are effective in promoting corrosion resistance of titanium against S. mutans, suggesting a promising strategy to enhance the stability of dental implants by endowing them with antibiofilm and anticorrosion properties.

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“…2 The process of symbiotic biofilm (dental plaque) formation involves multiple kinds of bacteria in the oral cavity, according to some certain sequences: for instance, the initial colonizing bacteria are accumulated in situ with the assistance of saliva and the gingival crevicular fluid; then, the interactions between the initial colonizing bacteria and the following-up bacteria through adhesins will mediate secondary colonization, etc. 3,4 Periodontitis is typically a chronic disease caused by plaque accumulation, which can lead to inflammatory infiltration, periodontal collagen breakdown, and even tooth loss. 5 Porphyromonas gingivalis, a key pathogen of periodontitis, is a representative of secondary colonizing bacteria in dental plaque.…”

Section: Introductionmentioning

confidence: 99%

Efficient clearance of periodontitis pathogens by S. gordonii membrane-coated H₂O₂ self-supplied nanocomposites in a “Jenga” style

et al. 2023

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Succession of oral bacterial colonizers on dental implant materials: An in vitro biofilm model

Cited by 13 publications

References 82 publications

Veillonella parvula: An update from a stomatological point of view

Veillonella parvula: An update from a stomatological point of view

Antibiofilm peptides enhance the corrosion resistance of titanium in the presence of Streptococcus mutans

Efficient clearance of periodontitis pathogens by S. gordonii membrane-coated H₂O₂ self-supplied nanocomposites in a “Jenga” style

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Succession of oral bacterial colonizers on dental implant materials: An in vitro biofilm model

Cited by 13 publications

References 82 publications

Veillonella parvula: An update from a stomatological point of view

Veillonella parvula: An update from a stomatological point of view

Antibiofilm peptides enhance the corrosion resistance of titanium in the presence of Streptococcus mutans

Efficient clearance of periodontitis pathogens by S. gordonii membrane-coated H2O2 self-supplied nanocomposites in a “Jenga” style

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Product

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Efficient clearance of periodontitis pathogens by S. gordonii membrane-coated H₂O₂ self-supplied nanocomposites in a “Jenga” style