Succinic Acid – A Model Building Block for Chemical Production from Renewable Resources

Werpy, Todd A.; Frye, John G.; Holladay, John

doi:10.1002/9783527619849.ch30

Cited by 16 publications

(19 citation statements)

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“…It is considered that the promising process should imply the fermentation without any titration agent or with its limited use where the free SA is the main product (Yuzbashev et al 2011). However, the traditional producers of SA, bacteria A. succiniciproducens, A. succinogenes, M. succiniciproducens, recombinant strains of E. coli, and C. glutamicum, should be cultivated at neutral pH, since at lower pH (5-6), significant amounts of by-products (acetate, formate, ethanol, and others) are accumulated (Zeikus et al 1999;Carole et al 2004;Werpy et al 2006;McKinlay et al 2007;Bechthold et al 2008;Bozell and Petersen 2010;Cheng To maintain optimal pH value, it is necessary to add KOH, NaOH, and other bases which react with SA; as a result, SA salts are produced rather than the desired free SA; therefore, additional stage of medium acidifying was required before the SA extraction.…”

Section: Discussionmentioning

confidence: 99%

“…The microbiological synthesis of SA is considered as more perspective due to its ecological and economical advantages (Zeikus et al 1999;Carole et al 2004;Werpy et al 2006;McKinlay et al 2007;Bechthold et al 2008;Bozell and Petersen 2010). The SA production is mostly based on the use of bacteria, such as Anaerobiospirillum succiniciproducens, Actinobacillus succinogenes, Mannheimia succiniciproducens, Escherichia coli, and Corynebacterium glutamicum (Zeikus et al 1999;Carole et al 2004;Werpy et al 2006;McKinlay et al 2007;Bechthold et al 2008;Sauer et al 2008;Bozell and Petersen 2010;Cheng et al 2012).…”

Section: Introductionmentioning

confidence: 99%

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The production of succinic acid by yeast Yarrowia lipolytica through a two-step process

Kamzolova

Vinokurova

Shemshura

et al. 2014

Appl Microbiol Biotechnol

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The production of α-ketoglutaric acid by yeast Yarrowia lipolytica VKMY-2412 from ethanol and its subsequent chemical conversion to succinic acid (SA) were investigated. A highly effective and environmentally friendly process of α-ketoglutaric acid production was developed using a special pH-controlling strategy, in which the titration of the culture broth with KOH in the acid-formation phase was minimal, that allowed accumulation of only low amounts of inorganic wastes in the course of SA recovery. The culture broth filtrate containing α-ketoglutaric acid (88.7 g l(-1)) was directly employed for SA production; the amount of SA produced comprised 71.7 g l(-1) with the yield of 70% from ethanol consumed. SA was isolated from the culture broth filtrate in a crystalline form with the purity of 100%. The yield of isolated SA was as high as 72% of its amount in the culture broth filtrate. The antimicrobial and nematocidic effects of SA of microbial origin on pathogenic organisms that cause human and plant diseases were revealed for the first time.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

The production of succinic acid by yeast Yarrowia lipolytica through a two-step process

Kamzolova

Vinokurova

Shemshura

et al. 2014

Appl Microbiol Biotechnol

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“…Taking into account the neutral and salty nature of cultivation broth, diammonium succinate is considered to be the bio-based raw material for chemical syntheses. Although different conversion reactions of N-containing succinates (Werby et al, 2006) have been investigated, industrial processes based on fermentation broths have not been realized so far. As long-term objective of R&D work the production of polyamide-44 or polyamide-4 from succinic acid and its derivatives 1,4-diaminobutane and 2-pyrrolidinone is aspired.…”

Section: Production Of Succinic Acid From Renewable Resources As a C4mentioning

confidence: 99%

Coupled production in biorefineries—Combined use of biomass as a source of energy, fuels and materials

Lyko

Deerberg

Weidner

2009

Journal of Biotechnology

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“…Nowadays succinic acid can be obtained from the fermentation of sugars, and is becoming one of the most important value added chemicals from biomass from which many other industrially important chemicals can be derived [75][76][77][78].…”

Section: Poly(butylene Succinate)mentioning

confidence: 99%

Permeability in Clay/Polyesters Nano-Biocomposites

Sorrentino

Gorrasi

Vittoria

2012

Environmental Silicate Nano-Biocomposites

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In this chapter we focus on the barrier properties of nanocomposite of biodegradable polyesters with layered inorganic fillers. First of all, to better understand the influence of the lamellar inorganic fillers on the permeability, the theory of permeation and the barrier models so far developed for polymer nanocomposites are reviewed. Afterwards the barrier properties of the most important biodegradable polyesters filled with inorganic lamellar solids, such as Polylactic acid (PLA), Polycaprolactone (PCL), Polyhydroxbutyrate (PHB), and Polybutylenesuccinate (PBS) are reviewed and the outstanding results enlightened. As a general trend, the best improvement of barrier properties is related to the exfoliation of clay platelets into the polymeric matrix, and this in turn is dependent on the chemical structure of the clay, the organic modification, the filler concentration and the processing procedure to prepare the composite. Where possible, all these parameters were reported and correlated with the final properties. Also the contrasting effect of clays on the two parameters determining the water permeability, that is sorption and diffusion, is reported in many cases.

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Succinic Acid – A Model Building Block for Chemical Production from Renewable Resources

Cited by 16 publications

References 0 publications

The production of succinic acid by yeast Yarrowia lipolytica through a two-step process

The production of succinic acid by yeast Yarrowia lipolytica through a two-step process

Coupled production in biorefineries—Combined use of biomass as a source of energy, fuels and materials

Permeability in Clay/Polyesters Nano-Biocomposites

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