Sudden and unexpected and near death during the early neonatal period: A multicenter study

Tsao, Pei Chen; Chang, Fu; Chen, Shu Jen; Soong, Wen‐Jue; Jeng, Mei Jy; Lee, Yu Sheng; Yen, Hsiu Ju; Yang, Chia Feng; Tang, Ren-Bin

doi:10.1016/j.jcma.2011.12.009

Cited by 5 publications

(2 citation statements)

References 19 publications

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“…However, interpretations must be made with caution as the inclusion criteria differ widely. Some studies only include SIDS, unexplained deaths occurring <2 h [15–17], while other reports include early-unexpected ALTE events during first week of life also when a plausible etiology is found after postevent investigations [18, 19]. …”

Section: Resultsmentioning

confidence: 99%

Sudden Unexpected Postnatal Collapse of Newborn Infants: A Review of Cases, Definitions, Risks, and Preventive Measures

Herlenius

Kuhn

2013

Transl. Stroke Res.

105

100

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This study aimed to review available published reports concerning sudden unexpected postnatal collapse (SUPC) of apparently healthy infants within the first days of postnatal life, establish a structured presentation and delineate recommendations for preventive measures. All published reports of SUPC cases were retrospectively analyzed, and three not previously published SUPC cases at Karolinska University Hospital were detailed to exemplify the varying presentations and outcomes of SUPC. We found 398 published cases of SUPC occurring during first postnatal week. Estimated incidence of the SUPC of a presumably healthy infant after birth differs widely, ranging from 2.6 cases to 133 cases/100,000. However, definition, inclusion, and exclusion criteria vary substantially between reports. Our summary indicates that reported SUPC occurs more frequently than expected from recent surveys. About half of the infants die, and of the remaining survivors, half have neurological sequela. Of the 233 cases of sudden unexpected death described, no etiology was found in 153 cases. When a defined time for the SUPC event is described, approximately one third of reported events occur during the first 2 h, between 2 and 24 h and between 1 and 7 days after birth, respectively. Adequate education of caregivers and appropriate surveillance during the first days of newborns should enable us to save hundreds of lives.

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Section: Resultsmentioning

confidence: 99%

Sudden Unexpected Postnatal Collapse of Newborn Infants: A Review of Cases, Definitions, Risks, and Preventive Measures

Herlenius

Kuhn

2013

Transl. Stroke Res.

105

100

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“…Some reports consider SUPC occurring within the first 7 days of life. [22][23][24][25][26] Others take into account only the critical events occurring in the first 24 hours from birth, where the SUPC incidence was estimated at 2.6/100,000 live births. 2,4 The studies that have analyzed the SUPC episodes arising within the first 3 hours of life report that they usually occur during the newborn nursing or during skin-to-skin contact with the mother, 4,5 as also happened in our newborns.…”

Section: Discussionmentioning

confidence: 99%

Incidence of Sudden Unexpected Postnatal Collapse in the Therapeutic Hypothermia Era

et al. 2017

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Objective Hypothermia is considered the treatment of choice for newborns with hypoxic-ischemic encephalopathy. Even though currently no consensus exists regarding the opportunity to extend this treatment also to newborns with sudden unexpected postnatal collapse (SUPC), this treatment is frequently adopted. The aim of the study was to evaluate whether the availability of hypothermia also for collapsed newborns in a tertiary level center may impact the estimated incidence of SUPC. Study Design A retrospective study was performed comparing the number of newborns admitted with the diagnosis of SUPC in the tertiary referral Neonatal intensive care unit of Florence in the period before (2008–2010) and after (2011–2014) the introduction of hypothermia treatment for newborns with SUPC. Result After introducing active cooling also to newborns with SUPC, the number of newborns with SUPC admitted to our center augmented and, consequently, SUPC incidence apparently increased from 5.3 to 15.5/100,000 live births, even though this difference did not reach statistical significance (odds ratio = 0.340; 95% confidence interval = 0.071–1.639; p = 0.179). Conclusion The apparent increase of SUPC incidence is probably related to a more effective centralization of newborns in our referral center but suggests that the real incidence of SUPC is probably significantly higher than currently estimated.

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Sudden Unexpected Postnatal Collapse

Monnelly¹,

Becher²

2020

Emerging Topics and Controversies in Neonatology

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Sudden and unexpected and near death during the early neonatal period: A multicenter study

Abstract: More effort on promotion of autopsy to discover the underlying disease is necessary and helpful. To build up an alarm system or protocol for education and early detection is the basis to prevent this tragedy.

Cited by 5 publications

References 19 publications

Sudden Unexpected Postnatal Collapse of Newborn Infants: A Review of Cases, Definitions, Risks, and Preventive Measures

Sudden Unexpected Postnatal Collapse of Newborn Infants: A Review of Cases, Definitions, Risks, and Preventive Measures

Incidence of Sudden Unexpected Postnatal Collapse in the Therapeutic Hypothermia Era

Sudden Unexpected Postnatal Collapse

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