1974
DOI: 10.1161/01.cir.50.4.780
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Sudden Death as a Complication of Anomalous Left Coronary Origin From the Anterior Sinus of Valsalva

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Cited by 711 publications
(357 citation statements)
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“…The special configuration of the ostium and the elastic type artery in the beginning of the RC (small aorta) probably keeps the ostium and the artery open during the cardiac cycle. The orifice was not collapsed as a slit-like ostium and there was no diastolic entrapment from the initial investment in aortic adventitia as referred to in the literature (Cheitlin et al, 1974;Roberts et al, 1982;Mahowald et al, 1986;Ness and McManus, 1988;Lipsett et al, 1994;Rinaldi et al, 1994;Becker, 1995).…”
Section: Discussionmentioning
confidence: 77%
“…The special configuration of the ostium and the elastic type artery in the beginning of the RC (small aorta) probably keeps the ostium and the artery open during the cardiac cycle. The orifice was not collapsed as a slit-like ostium and there was no diastolic entrapment from the initial investment in aortic adventitia as referred to in the literature (Cheitlin et al, 1974;Roberts et al, 1982;Mahowald et al, 1986;Ness and McManus, 1988;Lipsett et al, 1994;Rinaldi et al, 1994;Becker, 1995).…”
Section: Discussionmentioning
confidence: 77%
“…8 The majority of these complications may be exacerbated during or immediately after exercise, as exercise leads to compression of coronary arteries as well as increasing the preexisting angulation of the proximal portion of the anomalous vessel. 9 Clinical presentation of these patients ranges from asymptomatic for non-significant anomalies to syncope, chest pain, myocardial infarction and sudden cardiac death in significant anomalies. Diagnosis of anomalous coronary arteries may be suggested by echocardiography and a high index of suspicion.…”
Section: Discussionmentioning
confidence: 99%
“…These events are probably because of myocardial ischaemia even in the absence of atherosclerosis. An association with coronary events has been well documented for the case of a left coronary branches arising from a single RCA and coursing between the aorta and the pulmonary artery (intertruncal course) [9,10]. The pathophysiological mechanism in this scenario is most likely a transient occlusion of coronary artery branches because of an increase in blood flow through the aorta and the pulmonary artery resulting in kinking or pinching of the vessel [11].…”
Section: Discussionmentioning
confidence: 99%