Sudden Death from Fulminant Acute Cerebellitis

Levy, Elad I.; Harris, Angelique; Omalu, Bennet; Hamilton, Ronald L.; Branstetter, Barton F.; Pollack, Ian F.

doi:10.1159/000050381

Cited by 65 publications

(42 citation statements)

References 9 publications

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“…It typically occurs as a primary infectious, post-infectious or post-vaccination disorder and mostly presents in early childhood. Usually AC is a benign and self-limiting disease [1]; however, when fulminant it may end in sudden death or give rise to severe cerebellar atrophy [2,3].…”

Section: Mri Findings In Acute Cerebellitismentioning

confidence: 99%

MRI findings in acute cerebellitis

Bruecker¹,

Claus²,

Demaerel³

et al. 2004

Eur Radiol

112

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Acute cerebellitis is an inflammatory process involving the cerebellum. We report the clinical, CT and MRI features of four cases and a review of the literature. Bilateral diffuse hemispheric abnormalities represent the most common imaging presentations. Our observations demonstrate the various imaging appearances of acute cerebellitis. Simultaneous involvement of both hemispheres and the vermis has not been reported previously. The development of cerebellar atrophy following an initial normal MR imaging examination is also a new finding. In atypical clinical presentation, MR imaging can lead to the diagnosis. MR imaging findings have, however, no prognostic value.

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Section: Mri Findings In Acute Cerebellitismentioning

confidence: 99%

MRI findings in acute cerebellitis

Bruecker¹,

Claus²,

Demaerel³

et al. 2004

Eur Radiol

112

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show abstract

“…Medical therapeutic options are generally sufficient for nonprogressive cases and steroids may reduce the need of neurosurgical interventions in some cases [14,15]. On the other hand, some patients do not respond external ventricular drainage combined with steroid treatment and there may be fatal issues despite this treatment [16,17]. Posterior fossa decompression may be needed in these cases.…”

Section: Discussionmentioning

confidence: 99%

Acute Cerebellitis with Cerebellar Swelling Successfully Treated with Standard Dexamethasone Treatment

et al. 2008

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Although cerebellitis is common in childhood but cerebellitis with cerebellar swelling is rarely reported. Pulsed high dose methylprednisolone treatment is the choice of treatment for cases who have non-progressive symptoms. An 8-year-old girl presented acutely with vertigo, headache, and vomiting. Brain magnetic resonance imaging showed marked bilateral cerebellar swelling with increased signal on T2-weighted imaging. Following treatment with standard dexamethasone dose, the clinical and radiological signs resolved in 1 week. We conclude that standard dexamethasone treatment should be used in mild cases of acute cerebellitis in order to avoid adverse reactions of pulsed high dose methylprednisolone treatment.

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“…[30][31][32] Hence, acute cerebellitis and probably also acute cerebellar ataxia are likely distinct from acute demyelinating encephalomyelitis. The most severe cases of acute cerebellitis may present with clinical manifestations related to raised intracranial pressure resulting from cerebellar swelling and acute hydrocephalus, which overshadow manifestations of cerebellar dysfunction.…”

Section: Desai and Mitchell 1483mentioning

confidence: 99%

Acute Cerebellar Ataxia, Acute Cerebellitis, and Opsoclonus-Myoclonus Syndrome

2012

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Acute cerebellar ataxia and acute cerebellitis represent a process characterized by parainfectious, postinfectious, or postvaccination cerebellar inflammation. There is considerable overlap between these entities. The mildest cases of acute cerebellar ataxia represent a benign condition that is characterized by acute truncal and gait ataxia, variably with appendicular ataxia, nystagmus, dysarthria, and hypotonia. It occurs mostly in young children, presents abruptly, and recovers over weeks. Neuroimaging is normal. Severe cases of cerebellitis represent the other end of the spectrum, presenting with acute cerebellar signs often overshadowed by alteration of consciousness, focal neurological deficits, raised intracranial pressure, hydrocephalus, and even herniation. Neuroimaging is abnormal and the prognosis is less favorable than in acute cerebellar ataxia. Acute disseminated encephalomyelitis may be confused with acute cerebellitis when the clinical findings are predominantly cerebellar, but lesions on neuroimaging are usually widespread. Paraneoplastic opsoclonus-myoclonus syndrome is often initially misdiagnosed as acute cerebellar ataxia, but has very specific features, course, and etiopathogensis.

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Sudden Death from Fulminant Acute Cerebellitis

Cited by 65 publications

References 9 publications

MRI findings in acute cerebellitis

MRI findings in acute cerebellitis

Acute Cerebellitis with Cerebellar Swelling Successfully Treated with Standard Dexamethasone Treatment

Acute Cerebellar Ataxia, Acute Cerebellitis, and Opsoclonus-Myoclonus Syndrome

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