Sudden infant death syndrome: a critical review of approaches to research

Major epidemiological changes in sudden infant death syndrome: a 20-year population-based study in the UK

“…There are clues in pathology as to why SIDS occurs but these have previously been thought to be too general for diagnostic purposes [26]. …”

Sudden infant death syndrome and perinatal risk factors

“…It takes at least four days for astrogliosis to develop, which suggests that this is not an acute event [14]. It is considered that SIDS includes neurologically compromised newborns who do not possess developed compensation mechanisms during sleep and who experienced hypoxic attacks and alterations of neurotransmitter receptors in brain regions responsible for cardiovascular control during their fetal life [7,15,16]. Protracted prenatal or postnatal hypoxia that is concretely caused by active or passive nicotine intake was found in our material in 80 % of cases, which confirms previous theories of SIDS occurrence and smoking as a significant factor of neurotransmitter system disturbances [3,16].…”

Rapid Tests for Detection of Main Clostridial Toxins

“…Alpha toxin has been linked to human and other animal sudden infant death syndrome and numerous human deaths related to food poisoning by type A [207][208][209]. Since premature diagnosis and harsh treatment are the solution to decreasing morbidity and mortality, development of a rapid sensitive assay for detect and measure C. perfringens alpha toxin is necessary.…”