Background: To investigate political participation by dental hygiene students and analyze the differences therein based on the learning efficacy of dental hygiene policy. Methods: A total of 239 dental hygiene students who were expected to graduate responded to the survey. The data were collected online using a structured questionnaire consisting of 6 items on general characteristics, 10 on political participation, and 15 on the learning efficacy of dental hygiene policy. Statistical analysis was performed using SPSS 23.0. Political participation based on the learning efficacy of dental hygiene policy was analyzed using independent t-tests, ANOVA, and multiple regression analysis (p< 0.05). Results: Among the dental hygiene students, 60.7% voted in all three recent presidential, general, and local elections, and 14.2% did not. For political parties supported, 65.7% responded that they had "no supporting party," and 34.3% indicated that they had a "supporting party." In terms of the level of political participation of dental hygiene students (0∼50 points), the average score was 25.8 points, with the average passive political participation (0∼25 points) score at 15.6 points and the average active political participation (0∼25 points) score at 10.2 points. With an increase in dental hygiene policy learning efficacy, both passive and active political participation showed higher scores (p<0.05). Conclusion: Dental hygiene students showed low political participation. The presence of a supporting party, higher voting participation, and higher learning efficacy of dental hygiene policy were associated with higher passive and active political participation. Therefore, to increase this population's interest in political participation, various opportunities for related learning need to be promoted and provided in academia, leading to the enhancement of their political capabilities. In this manner, dental hygienists should expand their capabilities in various roles such as advocates, policy makers, and leaders.