Suicidal plant poisoning with Colchicum autumnale

Nagesh, K.R.; Menezes, Ritesh G.; Rastogi, Prateek; Naik, N.R.; Rasquinha, Jitesh Marian; Fazil, Abul

doi:10.1016/j.jflm.2011.04.008

Cited by 26 publications

(10 citation statements)

References 16 publications

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“…It conventionally manifests as gastroenterocolitis and may lead to multiple organ failure in fatal cases. [1] Although some experimental drugs are under investigation, their use is controversial. [2] Figure 1.…”

Section: Discussionmentioning

confidence: 99%

Acute colchicine toxicity: A case report

Dinçkal

Duman

2019

FNG & Demiroğlu Bilim Tıp Dergisi

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Colchicine is an alkaloid drug acquired from the autumn crocus (Colchicum autumnale) flower and is used as an antimitotic especially in the treatment of gout and Familial Mediterranean Fever (FMF). Its use in treating some rheumatic diseases (pseudogout, Behcet's disease, sarcoidosis, amyloidosis, etc.) as well as cancer treatment is under research. Although colchicine intoxication rarely occurs, therapeutic doses or suicidal overdose may lead to severe toxicity resulting in death. Clinical symptoms associated with colchicine overdose must be monitored in intensive care as they may show rapid progression. In this report, we present a 22-year-old patient with FMF who died from multiple organ failure shortly after suicidal overdose of colchicine.

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Section: Discussionmentioning

confidence: 99%

Acute colchicine toxicity: A case report

Dinçkal

Duman

2019

FNG & Demiroğlu Bilim Tıp Dergisi

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“…Estos casos han ocurrido, principalmente, como consecuencia del uso inadecuado por un error de medicació n o por intento autolítico [23][24][25] . Este hecho ha llevado a que agencias reguladoras como la Food and Drug Administration (FDA) en 2009 22 y la Agencia Españ ola de Medicamentos y Productos Sanitarios (AEMPS) en 2010 26 emitieran notas informativas alertando a los profesionales sanitarios de los riesgos del uso de este fá rmaco.…”

Section: Riesgos Y Recomendaciones En El Uso Clínico De La Colquicinaunclassified

Colquicina: ¿qué hay de nuevo, viejo?

2012

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“…Crude seeds were used for medical purposes (Sundov et al, 2005). Two to five hours after ingestion the patient develops nausea and diarrhoea, along with gastrointestinal symptoms (Gilotta and Brvar, 2010;Brvar et al, 2004;Nagesh et al, 2011;Brnčić et al, 2001;Sundov et al, 2005). In cases when patients consumed higher doses, they died of multi-organ dysfunction (Klintschar et al, 1999).…”

Section: Introductionmentioning

confidence: 99%

Adverse effects and intoxications related to medicinal/harmful plants

Vončina

Baričević

Brvar

2015

AAS

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Many wild plants around us have beneficial effects on our body and can be used as food. People are more and more interested in the medicinal plants. Many of them began gathering and preparing plants for the relief of symptoms of diseases or as a food dietary. Due to the lack of knowledge of plants, mistaking plants that contain toxins for medical plants may happen and cause adverse effects or even poisoning. The Poison Control Centre in Ljubljana keeps records of patients who have been admitted to the department because of adverse effects from the ingestion of certain plants. We analysed 64 cases, which were registered by the Poison Control Centre between January 2000 and December 2013. The aim of the present study was to determine which plants cause the most intoxications in Slovenia.Key words: medicinal plants, intoxication, misidentification, abuse, suicidal attempt IZVLEČEK ŠKODLJIVI UČINKI IN ZASTRUPITVE Z ZDRAVILNIMI/STRUPENIMI RASTLINAMIMnogo rastlin, ki nas obdaja, ima blagodejen vpliv na naše zdravje in so lahko dodatek k prehrani. Ljudje se vse bolj zanimajo za zdravilne rastline. Ljudje so začeli sami nabirati divje rastoče rastline in jih pripravljati za lajšanje bolezenskih simptomov ali kot dodatke k hrani. Zaradi nepoznavanja rastlin pa se lahko dogajajo zamenjave zdravilnih rastlin z rastlinami, ki vsebujejo strupene snovi in lahko povzročajo neželene učinke ali celo zastrupitve. Center za zastrupitve v Ljubljani beleži paciente, ki so bili sprejeti na njihov oddelek zaradi neželenih učinkov, ki so jih utrpeli po zaužitju nekaterih rastlin. Preverili smo 64 primerov, ki so bili zapisani na Centru za zastrupitve v časovnem obdobju od januarja 2000 do decembra 2013. Cilj raziskave je bil prikazati, katere rastline predstavljajo največji problem v Sloveniji.

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Suicidal plant poisoning with Colchicum autumnale

Cited by 26 publications

References 16 publications

Acute colchicine toxicity: A case report

Acute colchicine toxicity: A case report

Colquicina: ¿qué hay de nuevo, viejo?

Adverse effects and intoxications related to medicinal/harmful plants

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