Suicide attempts by self-poisoning in the United States among 10–25 year olds from 2000 to 2018: substances used, temporal changes and demographics

Spiller, Henry A.; Ackerman, J.P.; Smith, Gary A.; Kistamgari, Sandhya; Funk, Alexandra R.; McDermott, Michael R.; Casavant, Marcel J.

doi:10.1080/15563650.2019.1665182

Cited by 67 publications

(95 citation statements)

References 25 publications

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“…Studies have shown that self-poisoning is the most common method of attempting suicide among adolescents 11,12 and that over-the counter medications are the most commonly used means. 13 Acetaminophenrelated mortality is higher in countries where unlimited quantities can be obtained. 14 However, it is important to note that the use of acetaminophen for self-poisoning is not merely related to its accessibility but also to its popularity and the availability of other methods.…”

Section: Discussionmentioning

confidence: 99%

At-a-glance - Trends in emergency department visits for acetaminophen-related poisonings: 2011–2019

Kaur

McFaull

Bang

2020

Health Promot Chronic Dis Prev Can

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We examined trends in emergency department (ED) presentation rates for acetaminophenrelated poisonings across Canada. A total of 27123 cases of poisoning were seen in the electronic Canadian Hospitals Injury Reporting and Prevention Program (eCHIRPP) sentinel sites between April 2011 and February 2019; of these, 13.7% were related to acetaminophen use. A significant decreasing trend for both sexes was observed for unintentional poisonings (males: −10.3%; females: −8.0%). For intentional poisonings, there was a significant decrease among females only (−5.9%). Females have consistently displayed higher rates of ED presentations for both unintentional and intentional poisoning.

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Section: Discussionmentioning

confidence: 99%

At-a-glance - Trends in emergency department visits for acetaminophen-related poisonings: 2011–2019

Kaur

McFaull

Bang

2020

Health Promot Chronic Dis Prev Can

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“…There has been a 60percentage surge in suicide rates globally over the last 40 years. Approximately 800,000 suicidal deaths occur in the world annually (Spiller et al, 2020). In Egypt, Aboul-Hagag et al (2013) estimated the incidence of suicide deaths that ranged from 0.16 to 0.35/ 100,000 people.…”

Section: Introductionmentioning

confidence: 99%

Suicidal Self Poisoning and Its Relation With Personality Traits Among Admitted Cases to Menoufia Poisoning Control Center.

El-Farouny

Helmy

2021

The Egyptian Journal of Forensic Sciences and Applied Toxicolog

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Introduction: Suicide has been ranked among the top ten major causes of death worldwide. Self-poisoning throughout all ages is listed as one of the principal causes of unnatural deaths. Aim: Analysis of the pattern of suicidal self-poisoning cases with emphasis on its relationship with personality traits among admitted cases to Menoufia Poisoning Control Center (MPCC). Method: This was a cross-sectional, prospective study conducted on 1069 cases of suicidal self-poisoned cases attended to MPCC in one year. Data were collected including sociodemographic criteria, type of poison used, the severity of cases according to poisoning severity score, reasons for committing suicide, and the outcome. A personality questionnaire was fulfilled, which consisted of five personality traits: Extroversion, Agreeableness, Neuroticism, Openness, and Conscientiousness. Results: Total number of 1069 suicidal self-poisoning cases were admitted to MPCC over one year. The highest number of them was between 10-20 years (38.4%). Females were more susceptible to suicidal poisoning than males. 78.7% were from rural areas; being single is a high-risk factor. The highest percentage of cases were students, and family troubles were the most common motive in attempting suicide, followed by economic and financial issues. Pesticides were the most used poison. 25.4% of cases were severe according to PSS, and the fatality rate reached 15.9%, where aluminum phosphide was the first claiming agent in this high death rate. Personality trait was a significant factor among people who attempted suicide with a significant difference regarding the gender and type of the used poison. Conclusion: Suicide self-poisoning is a considerable public health risk that should be given high attention; the most common age was between (10-20) years. Females were more susceptible than males. Most cases were from rural areas. Most of them were students, and family troubles were the most common motive for attempting suicide. Pesticides were the most used poison, and the fatality rate reached 15.9%. Personality traits are a significant risk factor among people who attempt suicide.

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“…For purposes of analysis, we combined moderate, major, death, and "unable to follow judged as potentially toxic" as "severe" outcomes and compared them to non-severe, which combined the remaining outcomes. 12 For the primary outcome, we used segmented regression of interrupted time series (ITS), an analysis that is a statistical modeling of interrupted time series data. ITS analysis was used to evaluate the changes of trend and level in the proportion of severe outcomes (moderate, major, death, and "unable to follow judged potentially toxic") in single-substance benzonatate exposures in the first time period (pre-DSC) vs the second time period (post-DSC).…”

Section: Methodsmentioning

confidence: 99%

“…ITS analysis was used to evaluate the changes of trend and level in the proportion of severe outcomes (moderate, major, death, and "unable to follow judged potentially toxic") in single-substance benzonatate exposures in the first time period (pre-DSC) vs the second time period (post-DSC). 12 Also, ITS was applied in the secondary outcomes which compare dose over time in milligrams and number of capsules. It was used to control for trends which may already exist prior to DSC intervention.…”

Section: Methodsmentioning

confidence: 99%

“…For the primary outcome, we used segmented regression of interrupted time series (ITS), an analysis that is a statistical modeling of interrupted time series data. ITS analysis was used to evaluate the changes of trend and level in the proportion of severe outcomes (moderate, major, death, and “unable to follow judged potentially toxic”) in single‐substance benzonatate exposures in the first time period (pre‐DSC) vs the second time period (post‐DSC) 12 . Also, ITS was applied in the secondary outcomes which compare dose over time in milligrams and number of capsules.…”

Section: Methodsmentioning

confidence: 99%

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Impact of a drug safety communication on the severity of benzonatate exposures reported to poison centers

Leonard

Seung

2020

Pharmacoepidemiology and Drug

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Purpose Identify if publication of the 2010 drug safety communication (DSC) regarding benzonatate was associated with a decrease in the incidence of severe benzonatate poisonings reported to United States poison centers. Methods This retrospective database study utilized the National Poison Data System to compare the incidence of severe benzonatate poisonings before and after the publication of a drug safety communication. We utilized interrupted time series analysis to compare 2000‐2010 (pre‐DSC) to 2012‐2019 (post‐DSC). Results There were 18 619 benzonatate exposures reported to US poison centers during the time period covered and 11 554 exposures were included. There was an increase in exposures throughout the time period. There was no difference in the incidence of severe outcomes in the two time periods. In the pre‐DSC era, rates of severe outcomes increased by 0.4% per year followed by an immediate non‐significant drop of 2.9% in incidence of severe outcomes (P = .15). Finally, the slope of severe outcomes in the post‐DSC era showed an increase of 0.3% per year, which was not significantly different from the pre‐DSC era (P = .78). Conclusion Publication of a Drug Safety Communication regarding the risks of benzonatate did not result in a decrease in the proportion of severe benzonatate poisoning reported to US poison centers. Deaths and other severe outcomes continued to occur at a similar rate after the publication.

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Suicide attempts by self-poisoning in the United States among 10–25 year olds from 2000 to 2018: substances used, temporal changes and demographics

Cited by 67 publications

References 25 publications

At-a-glance - Trends in emergency department visits for acetaminophen-related poisonings: 2011–2019

At-a-glance - Trends in emergency department visits for acetaminophen-related poisonings: 2011–2019

Suicidal Self Poisoning and Its Relation With Personality Traits Among Admitted Cases to Menoufia Poisoning Control Center.

Impact of a drug safety communication on the severity of benzonatate exposures reported to poison centers

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