Suitability of Fetal Tissues From Spontaneous Abortions and From Ectopic Pregnancies for Transplantation

Branch, D. Ware; Ducat, Lee; Fantel, Alan G.; Low, Walter C.; Zhou, Feng; Dayton, Delbert H.; Gill, Thomas J.; Bledsoe, Sharon B.; Chiang, Yung Hsiao; Chong, Sonny K. F.; Hainline, Bryan E.; Heifetz, Stephen A.; Kahlenbeck, Debra; Low, Qinyuan; Padilla, Lillie Mae; Palmer, Catherine G.; Peavy, Daniel; Blazer, Bruce; Blount, Jeffrey P.; Christianson, Judy; Chrysler, Gayl; Conrad, John A.; Coultrip, Laura; D’Ascoli, Peter; Eastlund, Ted; Forbes, J.; Gasser, Tom; Hirschel, Mark; Kearney, Warren; Kondoh, Takeshi; Jin, Ying; Maynard, S Fp I M; Miller, Jeff; Norris, Beverly; Okagaki, Takashi; Peterson, Anne; Pundt, Lisa L.; Sengupta, Ranjita; Verfaillie, Cathérine; Virnig, Beth A; Weese, Kathy; Williams, Preston P.; Feil, Kelly; Hayek, Alberto; Lee, Virginia; McCormack, Michael K.; Mcmorris, F. Arthur; Schwarz, S; Trojanowski, John Q.; Byrne, Janice L. B.; Ward, Kenneth; Hillier, Sharon; Hogan, Molly; Kapur, Raj P.; Krohn, Marijane A.; Leppig, Kathy; Mason, J. Tate; Mueller, Beth A.; Gage, Helen Newman; Norwood, Thomas H.; Rigley, Ted; Thwin, Soe Soe; Vick, Tara

doi:10.1001/jama.1995.03520250082038

Cited by 21 publications

(1 citation statement)

References 2 publications

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“…It is, however, unlikely that fetal cell lines will be useful in the near future because of the phenotypic and genotypic instability of primary cells in culture (15). Thus, it is highly probable that spontaneously aborted fetuses may be the only realistic source of fetal donor tissue for transplantation, and it would seem prudent to develop more rigorous and highly standardized methods of recovery of these tissues in well-organized banks.…”

Section: Introductionmentioning

confidence: 99%

Quo Vadis? Fetal Tissue Transplantation

Michejda

1996

Journal of Hematotherapy

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The epidemiology and biologic characteristics of fetal tissue harvested from elective and spontaneous abortions are reviewed. The use of fetal bone marrow obtained from second trimester lost pregnancies is discussed. Allogeneic fetal tissue transplantation carried out in utero is reviewed. Data on intrauterine transplantation of human fetal bone marrow obtained from second trimester lost pregnancies into baboon fetuses are presented. The viability of this tissue, its clonogenic efficiency, engraftment, use in the future, and banking are discussed.

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Section: Introductionmentioning

confidence: 99%

Quo Vadis? Fetal Tissue Transplantation

Michejda

1996

Journal of Hematotherapy

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Suitability of Fetal Tissue for Transplantation

Michejda¹

1995

JAMA

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edge, and skills necessary to communicate effectively with pa¬ tients and may be better prepared for the challenges of practice.Ultimately, these communication skills do not just enhance patient satisfaction, they also improve the quality of medical care. The highest quality care depends on physicians with up-to-date medical knowledge and the communication skills necessary to be compassionate healers.

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GMP-Grade Human Fetal Liver-Derived Mesenchymal Stem Cells for Clinical Transplantation

Larijani

Aghayan

Goodarzi

et al. 2014

Methods in Molecular Biology

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Stem cell therapy seems a promising avenue in regenerative medicine. Within various stem cells, mesenchymal stem cells have progressively used for cellular therapy. Because of the age-related decreasing in the frequency and differentiating capacity of adult MSCs, fetal tissues such as fetal liver, lung, pancreas, spleen, etc. have been introduced as an alternative source of MSCs for cellular therapy. On the other hand, using stem cells as advanced therapy medicinal products, must be performed in compliance with cGMP as a quality assurance system to ensure the safety, quality, and identity of cell products during translation from the basic stem cell sciences into clinical cell transplantation. In this chapter the authors have demonstrated the manufacturing of GMP-grade human fetal liver-derived mesenchymal stem cells.

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Suitability of Fetal Tissues From Spontaneous Abortions and From Ectopic Pregnancies for Transplantation

Abstract: Fetal tissues from spontaneous abortions and from ectopic pregnancies are quite limited as feasible sources for human transplantation therapy.

Cited by 21 publications

References 2 publications

Quo Vadis? Fetal Tissue Transplantation

Quo Vadis? Fetal Tissue Transplantation

Suitability of Fetal Tissue for Transplantation

GMP-Grade Human Fetal Liver-Derived Mesenchymal Stem Cells for Clinical Transplantation

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