Sulfation and depolymerization of a bacterial exopolysaccharide of hydrothermal origin

Guézennec, Jean; Pignet, Patricia; Lijour, Y.; Gentric, Emilie; Ratiskol, Jacqueline; Colliec-Jouault, Sylvia

doi:10.1016/s0144-8617(98)00006-x

Cited by 40 publications

(30 citation statements)

References 27 publications

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“…6 Compositional and methylation analyses (see Table 1) gave the same results as those previously reported. It can be underlined that sugar ratios were not stoichiometric and that the presence of some residues (like [!…”

Section: Native Epssupporting

confidence: 79%

Structural studies of the main exopolysaccharide produced by the deep-sea bacterium Alteromonas infernus

Roger

Kervarec

Ratiskol

et al. 2004

Carbohydrate Research

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The structure of the extracellular polysaccharide produced by the mesophilic species, Alteromonas infernus, found in deep-sea hydrothermal vents and grown under laboratory conditions, has been investigated using partial depolymerization, methylation analysis, mass spectrometry and NMR spectroscopy. The repeating units of this polysaccharide is a nonasaccharide with the following structure: [carbohydrate: see text].

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Section: Native Epssupporting

confidence: 79%

Structural studies of the main exopolysaccharide produced by the deep-sea bacterium Alteromonas infernus

Roger

Kervarec

Ratiskol

et al. 2004

Carbohydrate Research

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“…They are immunomodulatory agents which can be potentically used as a therapy in the immunocompromised host (Arena et al, 2004). After sulfation and depolymerization performed by acid hydrolysis or radical depolymerization of the EPSs (released by A. infernus ), the products can gain the highly sulfated (40 % ), low-molecular-weight (24 x 103 g mol q) fractions with very promising anticoagulant activity as heparin and can be useful in the treatment of lipamia and arteriosclerosis (Guezennec et al, 1998). On the other hand, HE800 (EPS produced by Vibrio diabolicus ) was shown to be a strong bonehealing material without inducing any inflammatory reaction.…”

Section: Applications In the Medical Industrymentioning

confidence: 99%

Exopolysaccharides from marine bacteria

Chi

Fang

2005

J Ocean Univ. China

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Microbial polysaccharides represent a class of important products of growing interest for many sectors of industry. In recent years, there has been a growing interest in isolating new exopolysaecharides (EPSs)-producing bacteria from marine environments, particularly from various extreme marine environments. Many new marine microbial EPSs with novel chemical compositions, properties and structures have been found to have potential applications in fields such as adhesives, textiles, pharmaceuticals and medicine for anti-cancer, food additives, oil recovery and metal removal in mining and industrial waste treatments, ere This paper gives a brief summary of the information about the EPSs produced by marine bacteria, including their chemical compositions, properties and structures, together with their potential applications in industry.

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“…There are many mesophiles that thrive in the vicinity of these unique environments, and have been found to form biofilms and produce various polysaccharides. Polysaccharides from the Alteromonas, Pseudoalteromonas, and Vibrio genera have been isolated from deep-sea hydrothermal vents, and represent novel bacterial exopolysaccharides (Table 1) in terms of their saccharide composition and structure [Guezennec, 1999;Guezennec, et al, 1998a;Guezennec, et al, 1998b;Raguenes, et al, 1991;Raguenes, etal, 1996;Rougeaux, etal, 1999a;Rougeaux, etal, 1999b;Rougeaux, etal, 1996;mid Rougeaux, etal, 1998]. …”

Section: Deep-sea Mesophilic Polysaccharidesmentioning

confidence: 99%

Significance of polysaccharides in microbial physiology and the ecology of hydrothermal vent environments

Pysz

Montero

Chhabra

et al. 2004

The Subseafloor Biosphere at Mid-Ocean Ridges

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Hyperthermophilic microorganisms (those with maximum growth temperatures of 90°C and above) are known to inhabit deep-sea hydrothermal vent environments and are suspected of being present in the associated subsurface biosphere. One characteristic of the growth physiology of many heterotrophic hyperthermophiles is the capacity to use complex polysaccharides (e.g., a-and P-linked glucans as well as non-glucan hemicellulases) as carbon and energy sources. Polysaccharides may also play an important ecological role in the deep-sea subsurface biosphere as the structural elements of biofilms harboring both heterotrophic and chemolithotrophic microorganisms, representing a range of growth temperatures. Genome sequence analysis of several hyperthermophiles indicates that the enzymatic machinery to synthesize and hydrolyze polysaccharides is present in this group of microorganisms. This is supported by the biochemical characteristics of glycosidases from hyperthermophiles in addition to the observation that several hyper thermophiles form biofilms in pure and co-culture. It remains to be seen if biofilms form the basis for a subsurface biosphere but this possibility seems likely given the physiological characteristics of several hyperthermophiles and mesophiles, repre sentative of microorganisms previously isolated from vent sites.

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Sulfation and depolymerization of a bacterial exopolysaccharide of hydrothermal origin

Cited by 40 publications

References 27 publications

Structural studies of the main exopolysaccharide produced by the deep-sea bacterium Alteromonas infernus

Structural studies of the main exopolysaccharide produced by the deep-sea bacterium Alteromonas infernus

Exopolysaccharides from marine bacteria

Significance of polysaccharides in microbial physiology and the ecology of hydrothermal vent environments

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