Sulfones. Ii. Derivatives of 4,4'-Diaminodiphenyl Sulfone

Puromycin. Synthetic Studies. Ii. The Position of Glycosidation on the 6-Dimethylaminopurine Moiety

“…The mixture was heated to boiling, cooled and filtered; yield, 86%, m.p., 228°dec. This compound did not hydrolyze to X, but was recovered unchanged, when heated at 50°in 96% sulfuric acid, a hydrolysis reaction usually useful for N-arylsulfonamides (5). Hydrochloric acid hydrolysis removed the methylmercapto group as expected (7).…”

The Iridium‐Catalyzed Synthesis of Symmetrically and Unsymmetrically Alkylated Diamines under Mild Reaction Conditions

“…Subsequently, the nitro group is reduced to the free amino function using hydrogen and Raney nickel. In a final reaction step, the protecting group has to be removed and gives 4‐[(4‐aminophenyl)sulfonyl]‐ N ‐propylaniline in an overall yield of 79% 16. The synthesis protocol developed by us allows us to isolate product 5b in a yield of 86% in only one step.…”

COMPOUNDS FOR CANCER RESEARCH. V. RADIOACTIVE SULFONAMIDES1

“…N-p-Tosylamino-p'-nitrophenyl sulfide. After this paper was prepared for publication an account of the preparation of this compound by Baker, Querry, and Kadish appeared (21). They reported m.p.…”