Sulphite oxidase gene expression in human brain and in other human and rat tissues

High Turnover Rates for Hydrogen Sulfide Allow for Rapid Regulation of Its Tissue Concentrations

“…Even if we assume that all cross-reacting bands correspond to active ETHE1, it is clear that the sum of band intensities in liver or kidney samples is significantly higher than in brain sample. The reported tissue abundance of other enzymes involved in H 2 S degradation [i.e., rhodanese and sulfite oxidase in mammals (28,45)] corresponds to the relative aerobic H 2 S degradation activity observed in our study.…”

Sulfite-mediated oxidative stress in kidney cells

“…Data from our laboratory showed low SO expression in human kidney compared with human liver [49]. An earlier report estimated that SO of human liver is only 10% to 20% of that of rat liver [50].…”

Using curcumin to prevent structural impairments of testicles in rats induced by sodium metabisulfite

“…Reduction of spermatozoa count, motility, and normal morphology in the current study was in accordance with other researches. Previous studies also reported some toxic impacts of sulfites on the reproductive system (Cabré et al, 1990[7]; Woo et al, 2003[23]). “Sulfating agents” are harmful because they release SO 2 , a toxin to mammal reproductive system, in the tissue.…”

“…Different tissues exhibit different sulfite oxidase activities. For instance, liver and kidney show high, whereas testicle shows very low sulfite oxidase activities (Cabré et al, 1990[7]; Woo et al, 2003[23]). The majority of previous work has only focused on the effects of sulfating agents of these structures on the brain, while few studies have been published on these effects on the testicle.…”