Sulpiride for treatment of delusion of parasitosis

Takahashi, Tohru; Ozawa, Hiroshi; Inuzuka, Shin; Harada, Yukiko; Hanihara, Tokiji; Amano, Naoji

doi:10.1046/j.1440-1819.2003.01165.x

Cited by 12 publications

(8 citation statements)

References 9 publications

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“…We abstracted data from case series and case reports on 92 patients with primary delusional parasitosis treated with typical antipsychoticss who met our selection criteria – (see Table DS2 (data supplement to online version of this paper) (Riding & Munro, 1975; Gould & Gragg, 1976; Munro, 1978 a , b , 1982; Frithz, 1979; Avnstorp et al , 1980; Ungvari, 1984; Berrios, 1985; Andrews et al , 1986; Sheppard et al , 1986; Ungvari & Vladar, 1986; May & Terpenning, 1991; Srinivasan et al , 1994; Chiu et al , 1996; Rasanen et al , 1997; Kim et al , 2003; Takahashi et al , 2003).…”

Section: Resultsmentioning

confidence: 99%

Antipsychotic treatment of primary delusional parasitosis

2007

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Section: Resultsmentioning

confidence: 99%

Antipsychotic treatment of primary delusional parasitosis

2007

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“…Another limited source of information about the neural basis of DI results from patients in whom symptoms developed secondary to localized brain lesions (ischemic lesions, tumors, etc.). Ischemic brain lesions in these patients were seen predominantly in subcortical regions and in temporo-parietal regions after stroke (2,37,68,90,97,195,242,244,278,314). Other case reports linked the origin of symptoms with a brain tumor in the hypophyseal region (30,183,217,219,315) or a craniopharyngioma (333).…”

Section: Pathophysiology Of DImentioning

confidence: 93%

“…Individual case reports with typical antipsychotics do not allow further statistics, but they show that a variety of antipsychotic substances have been used for DI over the last years, including chlorpromazine (304), haloperidol (7,15,46,172,255,293,304,351), fluphenazine (23), trifluoperazine (304), sulpiride (46,314), perazine (143), and thioridazine (19,172,251).…”

Section: Typical Antipsychoticsmentioning

confidence: 99%

Delusional Infestation

Freudenmann

Lepping²

2009

Clin Microbiol Rev

235

367

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SUMMARY This papers aims at familiarizing psychiatric and nonpsychiatric readers with delusional infestation (DI), also known as delusional parasitosis. It is characterized by the fixed belief of being infested with pathogens against all medical evidence. DI is no single disorder but can occur as a delusional disorder of the somatic type (primary DI) or secondary to numerous other conditions. A set of minimal diagnostic criteria and a classification are provided. Patients with DI pose a truly interdisciplinary problem to the medical system. They avoid psychiatrists and consult dermatologists, microbiologists, or general practitioners but often lose faith in professional medicine. Epidemiology and history suggest that the imaginary pathogens change constantly, while the delusional theme “infestation” is stable and ubiquitous. Patients with self-diagnosed “Morgellons disease” can be seen as a variation of this delusional theme. For clinicians, clinical pathways for efficient diagnostics and etiology-specific treatment are provided. Specialized outpatient clinics in dermatology with a liaison psychiatrist are theoretically best placed to provide care. The most intricate problem is to engage patients in psychiatric therapy. In primary DI, antipsychotics are the treatment of choice, according to limited but sufficient evidence. Pimozide is no longer the treatment of choice for reasons of drug safety. Future research should focus on pathophysiology and the neural basis of DI, as well as on conclusive clinical trials, which are widely lacking. Innovative approaches will be needed, since otherwise patients are unlikely to adhere to any study protocol.

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“…15 A limited number of case reports have documented the effectiveness of risperidone, 16,17 sulpiride, 18 and sertindole 19 in the treatment of DP. To our knowledge, this series of 3 case reports represents the first documentation of olanzapine's effectiveness in treating DP in the English-language dermatology literature.…”

Section: Commentmentioning

confidence: 99%