“…In-Storage Processing. Several works propose ISP designs as accelerators for different applications [88, (e.g., in machine learning [147,150,151], pattern processing and read mapping [91,149], and graph analytics [141]), generalpurpose [145,146,[152][153][154][155][156][157][158][159][160][161][162][163], bulk-bitwise operations using flash memory [164,165], in close integration with FPGAs [90,[166][167][168][169][170], or GPUs [171]. None of these works perform metagenomic analysis nor address the challenges of ISP for metagenomics.…”