Summary of effectiveness and impact of rotavirus vaccination with the oral pentavalent rotavirus vaccine: A systematic review of the experience in industrialized countries

Decline in rotavirus hospitalizations following the first three years of vaccination in Castile-La Mancha, Spain

“…Despite these drugs are not subsidized by the government, recent studies have estimated a significant decrease in rotavirus hospitalizations in Spain since their use became more widespread in 2008. [10][11][12][13] Other industrialized countries have already shown a reduction in hospital admissions after 1 to 2 y of a complete immunization schedule, [14][15][16] with the vaccine remaining effective up to 3 y after the last dose. 17,18 The aim of our research is to describe the burden borne by hospitals due to community-acquired rotavirus in CLM and its …”

Improvement in hospital Quality of Care (QoC) after the introduction of rotavirus vaccination: An evaluation study in Belgium

“…16 Rotavirus vaccination in countries with established vaccination programmes has consistently and significantly reduced the incidence of rotavirus gastroenteritis (RVGE) and associated hospitalizations, emergency department visits and outpatient/physician office visits in the United States (US), Europe and Australia. [17][18][19][20] Belgium introduced rotavirus vaccination in November 2006, with an uptake of 85% in the first year 21 and 89% in the second year.…”

Rotavirus vaccine: A cost effective control measure for India

“…Moreover, no available evidence suggests that either rotavirus diarrhea in US and many other developed nations without significant increase in risk of intussusception. [10][11][12][13][14] Likewise, promising efficacy of rotavirus vaccines was also shown in developing countries. [15][16][17] However, the efficacy was 10-50% lower in developing-country than in developed country settings 15,[18][19][20] and therefore efforts to strengthen healthcare systems must also accompany vaccine introduction.…”