Summary of the 2017 thyroid radiofrequency ablation guideline and comparison with the 2012 guideline

Kim, Ji-Hoon; Baek, Jung Hwan; Lim, Hyun Kyung; Na, Dong Gyu

doi:10.14366/usg.18044

Cited by 34 publications

(25 citation statements)

References 44 publications

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“…After RFA, the tissue of the ablation area would undergo heat coagulation necrosis, resulting in embolism of microcirculation and loss of blood supply. Thus, CEUS could accurately evaluate the extension of ablated area and the efficacy of the treatment, which was also stated in previous studies [27,28]. Besides, CEUS could also be used in locating the actual recurrent area in an enlarged nodule during follow-up and was valuable for an accurate second ablation.…”

Section: Discussionsupporting

confidence: 59%

Ultrasound-guided radiofrequency ablation for papillary thyroid microcarcinoma: a retrospective analysis of 198 patients

Luo

Tang

et al. 2020

International Journal of Hyperthermia

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Purpose: To evaluate the safety and efficacy of ultrasound-guided RFA for the treatment of papillary thyroid microcarcinoma (PTMC). Materials and methods: The data of 204 nodules from 198 PTMC patients who were treated using RFA were retrospectively reviewed in this study. Demographic variables, complication details and CEUS results in different time points were collected. The volumes and volume reduction rate (VRR) of the ablated area under CEUS at different follow-up time points were calculated and compared. Results: All the patients were successfully treated without major complication. Mild complications included cervical discomfort in three cases, postoperative cervical pain in one case, and transient hoarse voice in five cases. The volume of the ablated area in the 1st, 3rd, 6th, 12th, 18th and 24th month postoperatively were 241.7 ± 298.3mm 3 , 89.8 ± 147.2 mm 3 , 37.6 ± 87.2 mm 3 , 13.6 ± 59.8 mm 3 , 2.4 ± 14.4 mm 3 , and 0.2 ± 2.0 mm 3 respectively, with a statistically significant decrease (F ¼ 138.1, p ¼ .000), and the VRR in those time points were 73.9 ± 13.7%, 90.5 ± 8.2%, 96.1 ± 5.9%, 98.8 ± 3.2%, 99.6 ± 1.9% and 99.8 ± 1.0% respectively, with a statistically significant decrease (F ¼ 695.3, p ¼ .000). Conclusions: US-guided RFA is safe and effective for PTMC, with a good oncological outcome and VRR. Further randomized controlled prospective trials are still needed to compare the value of RFA and surgery.

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Section: Discussionsupporting

confidence: 59%

Ultrasound-guided radiofrequency ablation for papillary thyroid microcarcinoma: a retrospective analysis of 198 patients

Luo

Tang

et al. 2020

International Journal of Hyperthermia

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“…Some scientific societies have already incorporated the above mentioned ablation techniques into their guidelines for the treatment of thyroid nodules or have given specific recommendations for their application [9,[45][46][47] .…”

Section: Patient Informationmentioning

confidence: 99%

Non-Surgical and Non-Radioiodine Techniques for Ablation of Benign Thyroid Nodules: Consensus Statement and Recommendation

Feldkamp

Grünwald

Luster

et al. 2020

Exp Clin Endocrinol Diabetes

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Thyroid nodules and cysts are frequently diagnosed in Germany with a prevalence of about 20% in young adults reaching up to 70% in older adults. Surgery is the standard treatment of symptomatic nodules, nodules with suspicion of malignancy and thyroid cancer. Radioiodine treatment is applied for autonomously functioning nodules. During the last years new non-surgical and non-radioiodine techniques have been introduced to treat thyroid nodules. These techniques include ethanol/polidocanol treatment, radiofrequency, microwave, and laser ablation, and high frequency ultrasound ablation. A significant reduction in nodule size could be documented for these techniques in several studies, but long-term outcome data are missing. Until now, there is no general consensus regarding the appropriate indications for these methods. For this reason, the Thyroid Section (German Society for Endocrinology), the Thyroid Working Committee (German Society for Nuclear Medicine), and the German Association of Endocrine Surgeons (CAEK) for the German Society of General and Visceral Surgery (DGAV) reviewed the respective literature, discussed the pro and cons and developed a consensus statement and recommendation to help physicians and patients in their decision making.

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“…Image-guided non-surgical procedures such as ethanol ablation (EA) have been proposed as effective and less invasive approaches for the management of cystic (pure cystic) or predominantly cystic (cystic component > 50%) thyroid nodules causing pressure symptoms or complaints of neck bulging [1,2]. The Korean Society of Thyroid Radiology (KSThR) proposed strong recommendation of EA as first-line treatment method for cystic and predominantly cystic nodules that are not treated with simple aspiration [3].…”

Section: Introductionmentioning

confidence: 99%

“…Previous studies showed that EA achieved volume reduction for cystic (85-95% of cases) and predominantly cystic nodules (60-90% of cases) [4]; however, even though EA is known to be effective for reducing the volume of cystic or predominantly cystic thyroid nodules in most cases, they sometimes recur, and additional treatment needs to be considered [5][6][7][8]. For example, KSThR suggest radiofrequency ablation (RFA) for the incomplete resolved symptoms or recurrence following EA [3].…”

Section: Introductionmentioning

confidence: 99%

Recurrence and additional treatment of cystic thyroid nodules after ethanol ablation: validation of three proposed criteria

et al. 2021

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We evaluated three criteria for determining the need for additional treatment of cystic thyroid nodules after their recurrence following ethanol ablation (EA). Materials and Methods One hundred and fifty-four patients (M:F = 30:124; mean age, 53.4; range, 23-79 years) with 154 thyroid nodules (49 cystic and 105 predominantly cystic nodules) who presented between January 2014 and August 2017 were enrolled. All patients underwent follow-up ultrasonography (US) 1 month after EA, and were divided into therapeutic success and failure groups. The patients were evaluated according to three previously suggested criteria for recommending additional treatment: (1) nodules with ≥1 ml remnant fluid, (2) volume reduction <50%, (3) demonstration of solid component with vascularity. Results Thyroid nodules treated by EA showed significant volume reduction (18.4±21.6 to 4.2±6.5 [1-month follow-up] to 1.9±3.3 ml [final follow-up], p<0.001) and improvement in clinical problems. Additional treatment was unnecessary in 81%, 70%, and 71% of patients deemed as needing it according to the previously suggested criteria 1, 2, and 3, respectively. A c c e p t e d A r t i c l e Conclusion Additional treatment after EA should be decided according to the combination of clinical problems and US features. Understanding of this concept will be useful in planning for the further treatment strategy following US-guided EA.

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Summary of the 2017 thyroid radiofrequency ablation guideline and comparison with the 2012 guideline

Cited by 34 publications

References 44 publications

Ultrasound-guided radiofrequency ablation for papillary thyroid microcarcinoma: a retrospective analysis of 198 patients

Ultrasound-guided radiofrequency ablation for papillary thyroid microcarcinoma: a retrospective analysis of 198 patients

Non-Surgical and Non-Radioiodine Techniques for Ablation of Benign Thyroid Nodules: Consensus Statement and Recommendation

Recurrence and additional treatment of cystic thyroid nodules after ethanol ablation: validation of three proposed criteria

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