Sun-391 Histopathology Pattern of Renal Biopsy in Nephrotic Syndrome Patients: A Single Centre Study in Hasanuddin University Teaching Hospital, Makassar, South Sulawesi, Indonesia

Albaar, A.; Rasyid, Harun Al; Zatalia, S.R.; Kasim, Hasyim; Bakri, Sophie J.; Cangara, Husni

doi:10.1016/j.ekir.2020.02.931

Cited by 2 publications

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“…IgA Nephropathy remained a prominent cause of GN across the region, similar to findings across the world 32 . GN secondary to exposure to parasitic, bacterial and infective agents (mainly MPGN and post‐infectious GN) was common in middle‐ and lower‐income countries but was generally on the wane in developed countries due to improving socioeconomic changes and urbanization 33–35 . Indeed, studies from Singapore and Malaysia had shown a significant reduction in the incidence of MPGN in their cohorts over the last three decades 36,37 .…”

Section: Discussionmentioning

confidence: 99%

Clinical outcomes and performance indicators of patients with kidney failure and acute kidney injuries in ASEAN countries

2022

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Introduction This review article reports clinical outcomes and performance indicators of patients with kidney failure (KF) and acute kidney injuries (AKI) in Association of South East Asian Nations (ASEAN) countries. Methodology Association of South East Asian Nations data, segregated by income status, from national registries and literature were collated, compared and benchmarked against international references. Results The national incidence and prevalence of treated KF ranged from 172 to 479 per million population (pmp) and 36–2255 pmp, respectively. Brunei (79%), Malaysia (66%) and Singapore (66%) had world‐leading proportions of diabetes‐related KF. Hemodialysis (HD), Peritoneal Dialysis (PD) and transplant accounted for 68–100%, 0–27% and 0–18% of all KF replacement therapy, respectively. Transplant patient survival was superior with 90%–93% at 5 years and 71%–90% at 10 years, compared to PD (44%–54%) and HD (53–64%) at 5 years. Higher‐income countries were able to achieve good anemia control, HD and PD adequacy targets, while usage of arteriovenous fistula in HD varied from 70% to 85%. Acute Kidney Injury rates ranged from 24.2% to 49.2% of high‐dependency admissions. Lower incidences of PD peritonitis and HD catheter‐related Bloodstream Infections; and PD‐favouring quality‐of‐life were evident in higher‐income countries. Conclusion Association of South East Asian Nations has a challenging burden of kidney disease, with extremely high incidence, prevalence, DM‐related KF and AKI rates. The magnitude of the prevailing problem calls for the creation of a regional society under the auspices of ASEAN with a shared perspective of universal, equitable and charitable access to quality renal care; consistent with the founding premises and healthcare initiatives of ASEAN.

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Section: Discussionmentioning

confidence: 99%

Clinical outcomes and performance indicators of patients with kidney failure and acute kidney injuries in ASEAN countries

2022

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Kidney biopsy-based epidemiologic analysis shows growing biopsy rate among the elderly

Molnár

Thomas

Fintha

et al. 2021

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Systematic registration and examination of biopsy-related data in Central and Eastern Europe are scarce, while the health condition of the population is worse compared to other more developed countries. We aim to create a database and analyze the distribution and temporal variation of the renal biopsy diagnoses in Hungary, including the effect of the recent coronavirus pandemic. The diagnoses were standardized according to the recommendation of the European Renal Association. Native biopsy samples processed between January 1, 2006, and December 31, 2020, were analyzed. During the 15 years, 2140 native kidney biopsies were performed. The number of samples increased from 24.5 to 57.9 per million person-years and the median age from 37 to 51 years (p < 0.0001). The predominance of glomerular diseases was stable. The most frequent glomerulopathy was IgA nephropathy (21.5%), followed by focal segmental glomerulosclerosis (17.7%), and membranous nephropathy (15.7%). Trends showed the rise of ANCA-associated vasculitis. During the coronavirus pandemic, there was a decrease in the number of kidney biopsies and the proportion of membranous nephropathies. The diagnostic trends in our database showed increasing biopsy rates among the elderly and the growing frequencies of age-related diseases, which emphasizes the importance of altering medical focus according to demographic changes in this area.

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Sun-391 Histopathology Pattern of Renal Biopsy in Nephrotic Syndrome Patients: A Single Centre Study in Hasanuddin University Teaching Hospital, Makassar, South Sulawesi, Indonesia

Cited by 2 publications

References 0 publications

Clinical outcomes and performance indicators of patients with kidney failure and acute kidney injuries in ASEAN countries

Clinical outcomes and performance indicators of patients with kidney failure and acute kidney injuries in ASEAN countries

Kidney biopsy-based epidemiologic analysis shows growing biopsy rate among the elderly

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