Sunburn at the seaside

Diffey, Brian; Mobley, Curtis D.

doi:10.1111/phpp.12381

Cited by 12 publications

(13 citation statements)

References 3 publications

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“…UV indices on a horizontal surface, e.g., the back of a swimmer, at different depths in a typical ocean for solar altitudes of 90° (red curve) and 60° (black curve) corresponding to above-surface UV indices of 13.6 and 9.5, respectively, under clear sky conditions (modified from reference [23]).…”

Section: Figurementioning

confidence: 99%

Time and Place as Modifiers of Personal UV Exposure

Diffey

2018

IJERPH

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It is a common belief that, if we want to limit our sun exposure during outdoor recreational activities and holidays in order to avoid sunburn or reduce our risk of skin cancer, we need to reach for the bottle of sunscreen or cover up with clothing. As important as these measures are, there is another way to enjoy our time outdoors and still benefit from the experience. In this article, we consider the impact of time, place, and behaviour outdoors on our exposure to solar ultraviolet (UV) radiation. Some of the simple actions we can take in controlling our UV exposure include being aware of the position of the sun in the sky, understanding how we can use the UV index to guide our outdoor exposure, and the importance of reducing our sun exposure around the middle of the day. Finally we review our preferred holiday activities and destinations, and the influence of outdoor leisure pursuits. By planning where and when we spend our leisure time in the sun, we can maximise our enjoyment whilst limiting our UV exposure.

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Section: Figurementioning

confidence: 99%

Time and Place as Modifiers of Personal UV Exposure

Diffey

2018

IJERPH

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“…Photo-aged skin occurs due to UVA and UVB irradiation as UVC is stopped by the ozone layer. [9] Therefore, UVB is considered as the most harmful UV ray. [6,7] In addition, short-wave UVB photons are far more energetic than long-wave UVA photons, and DNA damage and sunburn are predominantly attributable to UVB.…”

Section: Introductionmentioning

confidence: 99%

Baicalein inhibits matrix metalloproteinase 1 expression via activation ofTRPV1‐Ca‐ERKpathway in ultraviolet B–irradiated human dermal fibroblasts

Huang

Chang

et al. 2019

Experimental Dermatology

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Increased matrix metalloproteinase 1 (MMP‐1) expression is a feature of photo‐aged skin. We investigated the effects of baicalein and sulphoraphane on ultraviolet B (UVB) irradiation–induced MMP‐1 expression and apoptosis using human dermal fibroblasts. UVB irradiation not only increased MMP‐1 expression, but also caused apoptosis. Both baicalein and sulphoraphane protected cells from UVB irradiation–induced apoptosis, but only baicalein inhibited MMP‐1 expression. UVB irradiation activated 12‐lipoxygenase, and its product, 12‐hydroxyeicosatetraenoic acid, activated TRPV1 channels. The resulting UVB irradiation–induced Ca2+ increase was blocked by the 12‐lipoxygenase inhibitor baicalein and the TRPV1 blocker capsazepine, but not by the Nrf2 inducer sulphoraphane. UVB irradiation also increased ROS generation and decreased Nrf2 protein levels. UVB irradiation–induced MMP‐1 expression was blocked by the Ca2+ chelator BAPTA, by capsazepine and by TRPV1 silencing. However, induction was unaffected by the antioxidant N‐acetylcysteine. ERK phosphorylation and JNK phosphorylation were induced by UVB irradiation, but only ERK phosphorylation was Ca2+ sensitive. Increased MMP‐1 expression was blocked by PD98059, but not by SP600125. Thus, increased MMP‐1 expression is mediated by increased cytosolic Ca2+ and ERK phosphorylation. UVB irradiation–induced ROS generation is also Ca2+ sensitive, and UVB irradiation–induced apoptosis is caused by increased ROS. Thus, baicalein, by blocking the UVB irradiation–induced cytosolic Ca2+ increase, protects cells from UVB irradiation–induced MMP‐1 expression and apoptosis. In contrast, sulphoraphane, by decreasing cellular ROS, protects cells from only UVB‐induced apoptosis. Thus, targeting 12‐lipoxygenase may provide a therapeutic approach to improving the health of photo‐aged human skin.

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“…On the other hand, sunlight intensity in the noon of midsummer is 130 times more than midwinter [53], and it was thought that UV rays are beneficial to acne. Therefore, sun-bath sustains the restoration of inflammatory lesions by increasing blood circulation [54,55].…”

Section: Discussionmentioning

confidence: 99%

Risk factor assessment for acne vulgaris in human and implications for public health interventions in north central India: A survey based study

Dikshit

Qidwai

Pandey

et al. 2017

Asian J Pharm Clin Res

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Objective: The aim of the present study is to deal with the population based field study regarding factors that might play essential role in occurrence or epidemiology of Acne vulgaris in north central India. Methods:This cross-sectional study was a population based field study. Populations were assessed for influence of various factors on acne prevalence. The study was carried out from April 2016 to October 2016 in north central India. For this survey, questionnaires were designed to cover all the required information regarding the incidence of acne that includes factors such as gender, age, skin type, complexion, season of the incidence, and dietary habit. Results: Acne vulgaris appears to be influenced by gender, age, seasonal variations, breakout area, complexion, skin types, and dietary habits. Further, the influence of dietary habit on acne, particularly the consumption of dairy products or high-carbon diet has also been evaluated. Apart from depicting the vulnerable range of age (p=0.003288), sensitivity on various skin types (P=0.00039) and complexion (P=0.001355) on the basis of gender; this field study on acne vulgaris, also reveals that the season has inordinate role in acne pervasiveness (P=0.115731). Conclusion:This study is helpful in categorizing the risk factors and manifesting the afflictions of acne in population thus, contributing health-care planning.

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Sunburn at the seaside

Cited by 12 publications

References 3 publications

Time and Place as Modifiers of Personal UV Exposure

Time and Place as Modifiers of Personal UV Exposure

Baicalein inhibits matrix metalloproteinase 1 expression via activation ofTRPV1‐Ca‐ERKpathway in ultraviolet B–irradiated human dermal fibroblasts

Risk factor assessment for acne vulgaris in human and implications for public health interventions in north central India: A survey based study

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