SUNCT Syndrome in the Elderly

Vikelis, Michail; Xifaras, Michail; Mitsikostas, DD

doi:10.1111/j.1468-2982.2005.00971.x

Cited by 14 publications

(11 citation statements)

References 18 publications

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“…in 1989 (1). SUNCT is predominant in men (2, 3), with a mean onset age of nearly 50 years (4); and for the most part, the aetiology and pathogenesis remain unknown.…”

Section: Introductionmentioning

confidence: 99%

Efficacy of Gabapentin in the Treatment of SUNCT Syndrome

Etemadifar¹,

Ghasemi³

et al. 2008

Cephalalgia

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This study was designed to evaluate the efficacy of gabapentin (GBP) in the treatment of SUNCT syndrome on a relatively large sample of Persian patients. Eight patients with SUNCT syndrome underwent a 4-week, open-label, daily treatment of 600-900 mg GBP. The frequency, intensity and duration of attacks were compared before and after the trial. After 4 weeks of treatment, intensity, duration and frequency of headaches were significantly (P < 0.05) reduced. In addition, five patients (62.5%) were completely relieved from headaches, and in the other three patients the mean intensity, frequency and duration of headaches were decreased notably. In this study, GBP was well tolerated and no unfavourable side-effects were reported. After the end of the trial all patients continued the medication, and after 3 months none reported undesired side-effects or return of the headaches to the pre-treatment status. Our patients had a significant response to GBP, and considering other case reports on the effectiveness of GBP in the treatment of SUNCT syndrome, we propose that, taking into account the good side-effect profile and lack of interactions of GBP, this drug could be considered as an option for the treatment of SUNCT.

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“…in 1989 (1). SUNCT is predominant in men (2, 3), with a mean onset age of nearly 50 years (4); and for the most part, the aetiology and pathogenesis remain unknown.…”

Section: Introductionmentioning

confidence: 99%

Efficacy of Gabapentin in the Treatment of SUNCT Syndrome

Etemadifar¹,

Ghasemi³

et al. 2008

Cephalalgia

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“…It is most often found in middle aged or older patients; the mean age at presentation is 50 years. The youngest patient to be diagnosed with SUNCT reported in the literature was 5 years old [ 3 ]; the oldest was 88 years old [ 4 ]. The onset of SUNCT is influenced by the seasons, as it presents most frequently in the spring and autumn [ 5 ].…”

Section: Discussionmentioning

confidence: 99%

“…Alcohol is not a trigger. Among TACs, SUNCT should be discriminated from cluster headache, paroxysmal hemicranias [ 13 ], and trigeminal neuralgia [ 4 ].…”

Section: Discussionmentioning

confidence: 99%

Botulinum Toxin A for the Treatment of a Child with SUNCT Syndrome

Zhang

Lian

et al. 2016

Pain Research and Management

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Background. Short-lasting unilateral neuralgiform headache with conjunctival injection and tearing (SUNCT) syndrome is an unusual cause of headache, mainly described in older adults, and is rare in children. Pain attacks may be severe, frequent, and prolonged. The therapeutic benefits of many drugs are disappointing. Patient and Methods. A 12-year-old boy suffered severe headache and toothache for 20 days. As treatment with nonsteroidal anti-inflammatory drugs, anticonvulsants, and steroids proved ineffective, he was treated with ipsilateral multisite subcutaneous injections of botulinum toxin A 70 U around the orbit, the temporal area, and the upper gum. Results. The pain had reduced in frequency and severity by the fourth day after treatment and had completely disappeared after 7 days. There were no side effects or recurrence during a subsequent 17-month follow-up period. Conclusion. Botulinum toxin A can be used to treat the first episode of SUNCT in children over the age of 12 years.

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“…The mean age at onset is around 50 years, but a few even later-onset cases are described, the oldest being 88 years [25].…”

Section: Short-lasting Unilateral Neuralgiform Headache With Conjunctmentioning

confidence: 98%