Sunrise in melanoma management: Time to focus on melanoma burden in Asia

<p>Clinical and Onychoscopic Features of Benign and Malignant Conditions in Longitudinal Melanonychia in the Thai Population: A Comparative Analysis</p>

“…In our study, Fitzpatrick's skin type 5 was significantly associated with SMIS, supporting previous studies that mentioned that ALM was commonly found among deeply pigmented skin. 21,23,24 Thumb, followed by hallux, were previously reported as the most commonly affected digits; 10,22,[24][25][26] however, our study as well as more recent studies did not find any of the digits affected. 11,17 Therefore, digit affected may not aid in the differentiation between malignant and benign causes of melanonychia.…”

Adjuvant therapy with nivolumab versus ipilimumab after complete resection of stage III/IV melanoma: Japanese subgroup analysis from the phase 3 CheckMate 238 study

“…Although not reflected in the baseline characteristic results in this study, melanoma presents differently in Asian patients compared with Caucasian patients because acral and mucosal subtypes are more predominant than cutaneous in Asian patients. 6 Analysis of melanoma subtypes in the overall population demonstrated that nivolumab could be less effective in patients with acral or mucosal melanoma than in those with cutaneous melanoma, 4 suggesting that data from the Japanese subpopulation be interpreted carefully, taking global data into consideration. Further research in Asian populations should be considered.…”

Merkel cell carcinoma in Taiwan

“…Although most MCC occurred in the body extremities in our study, none of the patients developed the disease in areas where acral melanoma is frequently found, indicating a different etiology between melanoma and MCC in Asian countries. [5] MCC frequently occurred in extremities and in the head and neck area, which are typical sun exposed areas. On the other hand, the frequency of appearance in the trunk was reduced, implying that MCC might be associated with chronic sun and UV exposure in our series.…”

“…Different epidemiology studies in Western and Asian countries showed a different incidence rate of malignancies such as melanoma, another aggressive skin cancer. [5] Most studies regarding MCC biologic origin, therapeutic strategies and outcomes were reported in Western countries, while reports for the disease in Asia are limited. [6–8] Some studies focused on epidemiology, such as prevalence of MCPyV [9] and chronic arsenicism, [10,11] but no study in Taiwan reported data about therapeutic treatments and disease outcomes.…”