[<sup>18</sup>F] FDG PET/CT can improve the diagnostic accuracy for aortic endograft infection

Brüls, Samuel; Hassani, Imane El; Hultgren, Rebecka; Hustinx, Roland; Courtois, Audrey; Dumortier, Amanda; Defraigne, Jean-Olivier; Sakalihasan, Natzi

doi:10.1080/00015385.2021.1949105

Cited by 4 publications

(1 citation statement)

References 29 publications

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“…Along with previous results, the time-to-infection did not influence basic uptake values; however, the type of initial operation (EVAR vs. OAR) might ( Table 2 ) [ 7 , 22 ]. Similar results have been reported from smaller cohort studies and meta-analyses and also after open ascending aortic repair [ 23 , 24 , 25 , 26 , 27 , 28 ]. Yet, quantitative PET analysis could be suggestive of perigraft gas bubbles, but no correlations with eventual bacteria and clinical outcomes of VGEI are reported [ 6 , 29 ].…”

Section: Discussionsupporting

confidence: 89%

Aortic Vascular Graft and Endograft Infection–Patient Outcome Cannot Be Determined Based on Pre-Operative Characteristics

Puttini,

Kapalla,

Braune

et al. 2024

JCM

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Vascular graft/endograft infection (VGEI) is a serious complication after aortic surgery. This study investigates VGEI and patient characteristics, PET/CT quantification before surgical or conservative management of VGEI and post-intervention outcomes in order to identify patients who might benefit from such a procedure. PET standard uptake values (SUV) were quantitatively assessed and compared to a non-VGEI cohort. The primary endpoints were in-hospital mortality and aortic reintervention-free survival at six months. Ninety-three patients (75% male, 65 ± 10 years, 82% operated) were included. The initial operation was mainly for aneurysm (67.7%: 31% EVAR, 12% TEVAR, 57% open aortic repair). Thirty-two patients presented with fistulae. PET SUVTLR (target-to-liver ratio) showed 94% sensitivity and 89% specificity. Replacement included silver-coated Dacron (21.3%), pericardium (61.3%) and femoral vein (17.3%), yet the material did not influence the overall survival (p = 0.745). In-hospital mortality did not differ between operative and conservative treatment (19.7% vs. 17.6%, p = 0.84). At six months, 50% of the operated cohort survived without aortic reintervention. Short- and midterm morbidity and mortality remained high after aortic graft removal. Neither preoperative characteristics nor the material used for reconstruction influenced the overall survival, and, with limitations, both the in-hospital and midterm survival were similar between the surgically and conservatively managed patients.

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Section: Discussionsupporting

confidence: 89%

Aortic Vascular Graft and Endograft Infection–Patient Outcome Cannot Be Determined Based on Pre-Operative Characteristics

Puttini,

Kapalla,

Braune

et al. 2024

JCM

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Endograft Infections

Moulakakis,

Mylonas

2024

Mastering Endovascular Techniques

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Exploring Thoracic Aortic Graft Infection: A Comprehensive Review of Diagnosis and Treatment Options with a Management Strategy Algorithm

O’ Sullivan,

Casey,

Sidhu

et al. 2024

Journal of Cardiac Surgery

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As surveillance and the diagnosis of pathology grow, increasing numbers of patients are undergoing major aortic interventions globally. As a result, surgeons and physicians will encounter thoracic aortic graft infections with increasing frequency. These infections are extremely challenging, high‐risk problems to deal with. This article provides a comprehensive overview of the pathogenesis, diagnosis, and management both medical and surgical of this high‐risk complication. We provide proposed diagnostic criteria and suggested algorithm for the management of this important group of patients.

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[¹⁸F] FDG PET/CT can improve the diagnostic accuracy for aortic endograft infection

Cited by 4 publications

References 29 publications

Aortic Vascular Graft and Endograft Infection–Patient Outcome Cannot Be Determined Based on Pre-Operative Characteristics

Aortic Vascular Graft and Endograft Infection–Patient Outcome Cannot Be Determined Based on Pre-Operative Characteristics

Endograft Infections

Exploring Thoracic Aortic Graft Infection: A Comprehensive Review of Diagnosis and Treatment Options with a Management Strategy Algorithm

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[18F] FDG PET/CT can improve the diagnostic accuracy for aortic endograft infection

Cited by 4 publications

References 29 publications

Aortic Vascular Graft and Endograft Infection–Patient Outcome Cannot Be Determined Based on Pre-Operative Characteristics

Aortic Vascular Graft and Endograft Infection–Patient Outcome Cannot Be Determined Based on Pre-Operative Characteristics

Endograft Infections

Exploring Thoracic Aortic Graft Infection: A Comprehensive Review of Diagnosis and Treatment Options with a Management Strategy Algorithm

Contact Info

Product

Resources

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[¹⁸F] FDG PET/CT can improve the diagnostic accuracy for aortic endograft infection