Org. Chem. Front.
 2024
DOI: 10.1039/d4qo01594k
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18F-labelling of nitrogen-containing aryl boronates – anti-cancer drug melflufen as a case study

Kevin Bajerke,
Fredrik Lehmann,
Gunnar Antoni
et al.

Abstract: 18F-Labelling of nitrogen-containing arenes via copper mediated radiofluorination (CMRF) was investigated. The studies targeted analogues of anti-cancer drug melflufen with an alkylating bis(2-chloroethyl)amino pharmacophore. Studies of melflufene anologues and various...

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