Supercritical CO₂ assisted extraction of essential oil and naringin from Citrus grandis peel: in vitro antimicrobial activity and docking study

Abstract

In this work, waste C. grandis peel was the ingredient used to extract essential oil and naringin by a supercritical CO2 technique. Both natural products were evaluated for antimicrobial activity and docking studies.

In vitro and in silico docking and molecular dynamic of antimicrobial activities, alpha-glucosidase, and anti-inflammatory activity of compounds from the aerial parts of Mussaenda saigonensis

“…4 to 5 . 25 Based on analyzing the docking interaction model, Fig. 7 , pose 90 interacted well with enzyme because three parts of pose 90 have exposed full interactions with such as functional group: Glu 325 to hydrogen atoms of hydroxyl groups, Leu 480 to hydrogen atom of hydroxyl phenolic, Tyr 312 to hydrogen atom of hydroxyl phenolic group, and Tyr 304 to oxygen and hydrogen atoms; capping group: pi–pi stacked interaction from Tyr 476 to pi electron system of phenyl group, and pi–alkyl or alkyl from Leu 480 to pi electron system of phenyl group; and linker part: Leu 480 to methyl group, and Tyr 476 to methyl of methoxy group.…”

“…4 to 5. 25 Based on analyzing the docking interaction model, Fig. 7, pose 90 interacted well with enzyme because three parts of Fig.…”