Supercritical CO2-based tailor made valorization of Origanum vulgare L extracts: A green approach to extract high-value compounds with applied perspectives

García‐Pérez, J. Saúl; Cuéllar‐Bermúdez, Sara P.; Quiroz, Reynaldo de la Cruz; Arévalo-Gallegos, Alejandra; Esquivel-Hernández, Diego; Rodríguez‐Rodríguez, José; García‐García, Rebeca; Iqbal, Hafiz M.N.; Parra‐Saldívar, Roberto

doi:10.1016/j.jenvman.2018.11.117

Cited by 13 publications

(12 citation statements)

References 49 publications

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“…With respect to the antimicrobial activity, F3, F4, Ooil, and Unoil were effective in inhibiting microbial growth and showed zones of inhibition diameters comparable with other publications [2,4,5,8,10]. The results of MIC are consistent with those obtained by the diffusion method.…”

Section: Discussionsupporting

confidence: 87%

“…The constituents and the concentration of essential oil compounds found in oregano generally vary due to a wide diversity of factors such as species, pests, soil conditions, harvest season, geographical location, climate, and growing conditions [2,5]. In addition, the drying method, the extraction technique and the anatomical part of the plant used for the extraction also influence the yield and composition of the essential oils [7,8,9]. Our work shows that an essential oil fractionated under different temperature and vacuum conditions contains a different profile of chemical compounds that directly influence the biological activities presented.…”

Section: Discussionmentioning

confidence: 99%

“…Furthermore, the results obtained against C. albicans indicate that the F4, Ooil and Unoil, have a good antifungal effect (diameter of inhibition of 4.3–4.5 cm) compared to that reported with the antifungal drug Amphotericin B (2.1 cm in diameter) [10]. The origin of the plant material, as well as the method of obtaining the essential oil fractions, were determinants for the antifungal activity, according to reports by García and collaborators who evaluated oregano oil extracted by supercritical fluids against the same strain of C. albicans and obtained less than 1 cm of inhibition [8].…”

Section: Discussionmentioning

confidence: 99%

“…In recent years, due to restrictions on the use of synthetic food additives and the constant increase in the survival capacity of detrimental microorganisms caused by resistance to antibiotics and preservatives, there has been an increase in the search for alternatives, such as natural antimicrobial compounds [4,5]. In this sense, the effectiveness of the antimicrobial action of oils and extracts depends to a large extent on the chemical composition, which is related to the species and the parts of the plant that are used, the growing conditions, the harvest and the processing, as well as the method to obtain the extracts [2,5,6,7,8,9].…”

Section: Introductionmentioning

confidence: 99%

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Chemical Composition and Biological Activities of Oregano Essential Oil and Its Fractions Obtained by Vacuum Distillation

et al. 2019

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Oregano (Poliomintha longiflora) essential oil (Ooil) is a product of high commercial value and many applications, including chemotherapy. Aiming to achieve the best use of this resource, the present study focuses on the characterization of separated fractions of Ooil by fractional vacuum distillation at low pressure. Four fractions (F1–F4) and undistilled oil (Unoil) were separated from Ooil and analyzed for their chemical composition and biological activities, such as antioxidant and antimicrobial activities. Gas chromatography–mass spectrometry shows differences in the composition among the fractions and Ooil. The amount of monoterpenes oxygenated (MO), sesquiterpenes hydrocarbon (SeH) and monoterpenes hydrocarbon (MH) varied between the fractions in ranges of 1.51–68.08, 3.31–25.12 and 1.91–97.75%, respectively. The major concentrations of MO and SeH were observed in F4 and Unoil. On the other hand, the highest concentrations of MH were found in F1 and F2, while the lowest were in F4 and Unoil. These results were correlated with the biological activity. Free-radical scavenging activity varied among fractions, with F4 and Unoil showing the highest activity. The antimicrobial test showed that F4 and Unoil had the highest activity in almost all cases. The correlation between the variables studied in the different fractions allows the definition of the particular properties for each one of them.

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Section: Discussionsupporting

confidence: 87%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Chemical Composition and Biological Activities of Oregano Essential Oil and Its Fractions Obtained by Vacuum Distillation

et al. 2019

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“…virens (Hoffm. et Link) letswarrt using scCO 2 in the presence of H 2 O. Pérez et al and Menaker et al’s studies determined that the addition of ethanol improves the oregano extraction yield significantly [ 18 , 19 ].…”

Section: Introductionmentioning

confidence: 99%

Enzymatic and Microwave Pretreatments and Supercritical CO2 Extraction for Improving Extraction Efficiency and Quality of Origanum vulgare L. spp. hirtum Extracts

Vladić

Duarte

Radman

et al. 2021

Plants

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The goal of the study was to establish a procedure for improving the efficiency of supercritical carbon dioxide (scCO2) extraction of Origanum vulgare L. spp. hirtum (Greek oregano) and enhancing the quality of obtained extracts. Microwave and enzymatic pretreatments of the plant material were applied prior to the scCO2 extraction. It was determined that the microwave pretreatment with irradiation power 360 W during 2 min accelerated the extraction of lipophilic compounds and provided a twofold higher extraction yield compared to the control. Moreover, this pretreatment also led to an increase in oxygenated monoterpenes content and the most dominant component carvacrol, as well as the extracts’ antioxidant activity. The enzymatic pretreatment caused a significant increase in the extraction yield and the attainment of the extract with the most potent antioxidant properties. Coupling the pretreatments with scCO2 extraction improves the process of obtaining high value lipophilic products of oregano in terms of utilization of the plant material, acceleration of the extraction with the possibility to adjust its selectivity and quality of extracts, and enhancement of biological activity.

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The Application of Supercritical Carbon Dioxide in the Extraction of Biomolecules

Cheikhyoussef

2020

Nanotechnology in the Life Sciences

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Supercritical CO2-based tailor made valorization of Origanum vulgare L extracts: A green approach to extract high-value compounds with applied perspectives

Cited by 13 publications

References 49 publications

Chemical Composition and Biological Activities of Oregano Essential Oil and Its Fractions Obtained by Vacuum Distillation

Chemical Composition and Biological Activities of Oregano Essential Oil and Its Fractions Obtained by Vacuum Distillation

Enzymatic and Microwave Pretreatments and Supercritical CO2 Extraction for Improving Extraction Efficiency and Quality of Origanum vulgare L. spp. hirtum Extracts

The Application of Supercritical Carbon Dioxide in the Extraction of Biomolecules

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