Supercritical fluid chromatography separation of chiral pesticides: Unique capabilities to study cyhalothrin and metalaxyl as examples

Cutillas, Víctor; García-Valverde, M.; Gómez-Ramos, María del Mar; Díaz-Galiano, Francisco José; Ferrer, Carmen María Salvador; Fernández‐Alba, Amadeo R.

doi:10.1016/j.chroma.2020.461007

Cited by 24 publications

(10 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Several interfaces have also been successfully applied, the most common approach being ESI-assisted with a liquid shell [63,66]. When MEKC is to be used, either non-volatile background electrolytes or the application of the partial fill technique should be used [67,68] Another technique to highlight for the analysis of pesticides is supercritical fluid chromatography (SFC) -considered as a hybrid of GC and LC-also coupled to MS [69,71], which is currently awakening in different fields as a result of the production of more robust and reliable instrumentation that has improved its reproducibility, robustness, specificity, and sensitivity [72,73]The use of supercritical fluids as mobile phases (i.e. supercritical carbon dioxide, the most common) allows rapid separations of pesticides of wide polarity due to the use of high flow rates with little or no consumption of organic solvents, which can be used as co-solvents [69,70].…”

Section: Analytical Methods For the Analysis Of Pesticide Residues In...mentioning

confidence: 99%

A Historical Review of the Use of Pesticides in Colombian Agriculture

Varela-Martínez¹,

Molina²,

Herrera³

2022

Preprint

View full text Add to dashboard Cite

The growing production and use of multiple types of pesticides in the agri-food sector has caused strong concern on the part of many organizations worldwide, which question the degree of safety and quality of the products being supplied to the population. Colombia, a geographically privi-leged country with extensive areas of agricultural use, is not apathetic to this situation. Therefore, this review article aims to give a citrus and updated vision of the use of pesticides worldwide and subsequently in the Colombian agricultural sector. As a result, a sector that is currently growing and contributing to the national economy was identified. However, with a strong tendency to use pesticides to maximize production yields and minimize associated costs. Currently, many pesti-cide residues are identified in transitional and high value crops, such as vegetables and fruits. This causes chronic and/or acute intoxication scenarios in populations that meet these substances. Finally, academia and the public sector seek to update knowledge that promotes the regulation and management of this type of substances, promoting the transformation of the sector towards organic and regenerative agri-food models that prohibit the implementation of pesticides for pest and disease control.

show abstract

Section: Analytical Methods For the Analysis Of Pesticide Residues In...mentioning

confidence: 99%

A Historical Review of the Use of Pesticides in Colombian Agriculture

Varela-Martínez¹,

Molina²,

Herrera³

2022

Preprint

View full text Add to dashboard Cite

show abstract

“…Cutillas et al [ 41 ] quantified the chiral pesticides cyhalothrin and metalaxyl by SFC hyphenated to MS detection. The ES of those compounds in SFC was performed on the commercial chiral columns Lux ® Cellulose-1 ( Table 1 ) and Lux ® Amylose-3 ( Table 2 ) (250 × 4.6 mm, i.d., 5 μm silica gel for all the columns).…”

Section: Cellulose-based Cspsmentioning

confidence: 99%

Polysaccharide- and β-Cyclodextrin-Based Chiral Selectors for Enantiomer Resolution: Recent Developments and Applications

Bui

Rosenau

2021

Molecules

View full text Add to dashboard Cite

Polysaccharides, oligosaccharides, and their derivatives, particularly of amylose, cellulose, chitosan, and β-cyclodextrin, are well-known chiral selectors (CSs) of chiral stationary phases (CSPs) in chromatography, because they can separate a wide range of enantiomers. Typically, such CSPs are prepared by physically coating, or chemically immobilizing the polysaccharide and β-cyclodextrin derivatives onto inert silica gel carriers as chromatographic support. Over the past few years, new chiral selectors have been introduced, and progressive methods to prepare CSPs have been exploited. Also, chiral recognition mechanisms, which play a crucial role in the investigation of chiral separations, have been better elucidated. Further insights into the broad functional performance of commercially available chiral column materials and/or the respective newly developed chiral phase materials on enantiomeric separation (ES) have been gained. This review summarizes the recent developments in CSs, CSP preparation, chiral recognition mechanisms, and enantiomeric separation methods, based on polysaccharides and β-cyclodextrins as CSs, with a focus on the years 2019–2020 of this rapidly developing field.

show abstract

“…Some evaluations of multiresidue methods have been performed using tandem mass spectrometry [19,20] and HRMS [21,22]. As pesticides are often chiral compounds, enantioseparation of pesticides by SFC-MS/MS was previously researched [23][24][25]. Since the commercialization of ultrahigh performance supercritical fluid chromatography, there is an increasing tendency to use this system for food analysis applications.…”

Section: Introductionmentioning

confidence: 99%

Liquid chromatography versus supercritical fluid chromatography coupled to mass spectrometry: a comparative study of performance for multiresidue analysis of pesticides

2021

Self Cite

View full text Add to dashboard Cite

Abundant studies have been published evaluating different parameters of reverse-phase liquid chromatography (LC) and supercritical fluid chromatography (SFC), both coupled to electrospray (ESI)/mass spectrometry (MS) for pesticide residue analysis. However, there is a lack of a comprehensive comparative study that facilitates deep knowledge about the benefits of using each technique. In the present study, the same mass spectrometer was used coupled to both liquid and supercritical fluid chromatographies with a multiresidue method of 215 compounds, for the analysis of pesticide residues in food samples. Through the injection of the spiked extracts, separate experiments were conducted. A study of the optimum ion source temperature using the different chromatography modes was performed. The results were evaluated in terms of sensitivity with tomato, leek, onion, and orange as representative fruit and vegetable matrices. The compounds which reported the highest area values in each chromatography were evaluated through their substance groups and polarity values. The impact of matrix effects obtained in tomato matrix was similar for both cases; however, SFC clearly showed better results in analyzing matrices with a higher number of natural co-extracted compounds. This can be explained by the combination of two effects: (i) chromatography separation and (ii) ion source efficiency. The chromatographic elution presented different profiles of matrix components, which had diverse impact on the coelution with the analytes, being more beneficial when SFC was used in the matrices studied. The data showed that the best results obtained in SFC are also related to a higher ionization efficiency even when the ESI emitter tip was not optimized for SFC flow. In the present study a comprehensive evaluation of the benefits and drawbacks of these chromatography modes for routine pesticide residue analysis related to target compounds/commodities is provided. Graphical abstract

show abstract

Supercritical fluid chromatography separation of chiral pesticides: Unique capabilities to study cyhalothrin and metalaxyl as examples

Cited by 24 publications

References 22 publications

A Historical Review of the Use of Pesticides in Colombian Agriculture

A Historical Review of the Use of Pesticides in Colombian Agriculture

Polysaccharide- and β-Cyclodextrin-Based Chiral Selectors for Enantiomer Resolution: Recent Developments and Applications

Liquid chromatography versus supercritical fluid chromatography coupled to mass spectrometry: a comparative study of performance for multiresidue analysis of pesticides

Contact Info

Product

Resources

About