2023
DOI: 10.3390/molecules28093903
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Supercritical Fluid Extraction of Essential Oil and Sclareol from a Clary Sage Concrete

Abstract: Clary Sage extracts are of industrial interest: in particular, sclareol shows a strong pharmaceutical potential. Supercritical fluid extraction was used to recover compounds of interest from a Salvia sclarea L. waxy n-hexane extract (“concrete”), using semi-continuous fractionation and a multi-step extraction strategy. Multi-step extraction experiments were carried out in two phases: the first one operated at 90 bar and 50 °C; the second one at 100 bar and 40 °C. GC-MS traces showed that during the first extra… Show more

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