were due to biofilm formation by normal skin flora at the time of prosthesis placement.The IA is an alternative to the retromandibular/transparotid approach to install the mandibular component of TMJ replacement devices. Its usage to treat noncomminuted mandibular fractures and to install reconstruction plates are well reported in the literature resulting in no external scarring, lower risk for injury to the facial nerve and parotid gland. 9,20,21 However, it is expected to increase infection rates, since devices will be exposed to oral bacteria during installation.Many protocols have been advocated to reduce the risk of TMJ replacement SSI infections. 15,17,19 Systemic intravenous antibiotic prophylaxis reduces the risk of postoperative infections when performed within 1 hour before surgical incision. 15 Broad spectrum antibiotics such as cefazolin, clindamycin, and cephalosporins are the most used preoperative antibiotics based on their good efficacy against staphylococcal species and uropathogens. 15,17,19 The antibiotics should be continued for 7 to 10 days postoperatively, especially for the high-risk patients. 15,[17][18][19] Irrigation with an antibiotic solution before and after implantation of the device components may also provide some assistance in decreasing the potential for local contamination. 15,18 The antibiotic protocol used in the 5 reported cases included prophylactic and postoperative intravenous cefazolin, combined with oral cephalexin after hospital discharge; in addition, copious irrigation of wounds with saline solution plus gentamycin was performed, which resulted in no case of postoperative SSI infection.The presented cases of benign tumor and severe condylar resorption represent indications of TMJ reconstruction with alloplastic prosthesis and the technical modification to install mandibular components seemed be safe and effective, despite the limited number of cases reported in this study. Customized implants associated with virtual planning allowed safer and easier surgery, decreasing surgical time and improving functional and aesthetics results. Yet, authors emphasize that appropriate selection of patients with careful diagnosis is critical to minimize the risk of TMJ prosthesis failure and postoperative complications.