Background: Soft tissue defects of the hand present a significant challenge in reconstructive surgery due to the hand's intricate anatomy and essential functional role. One of the main considerations in hand reconstruction is the choice of an appropriate flap. Among the various flaps used in hand reconstruction, the pedicled groin flap and the free anterolateral thigh flap have gained significant attention.Objective: This study aimed to compare between pedicled groin flap and free anterolateral thigh flap in complex hand defects reconstructions regarding patient demographics, flap outcomes, complication rates, donor site morbidities and hospitalization period.
Material and Methods: This multicenter prospective clinical trial was conducted from March 2021 to March 2022 on 20 patients with a clinical diagnosis of soft tissue defects of hand recruited from the