Superficial Depressed-Type Cancer Monitored by Colonoscopy through the Early Phase of Invasion

Baba, Yukino; Suzuki, Yoshio; Kobayashi, Masashi; Azumaya, Masaki; Takeuchi, Masaru; Shioji, Kazuhiko; Honma, Tomoki; Narisawa, Rintarou; Ajioka, Yoichi; Asakura, Hitoshi

doi:10.1055/s-2002-33564

Cited by 7 publications

(3 citation statements)

References 15 publications

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“…Different management strategies include resection, biopsy only or no treatment. Recently, an increasing rate of colorectal cancers <10 mm has been reported, 37–39 which warns us to look out for small lesions and, more importantly, treat them selectively. In summary, a method to determine the character of the lesion during colonoscopy is greatly needed and MCC could fulfill this role.…”

Section: Discussionmentioning

confidence: 99%

Further validation of magnifying chromocolonoscopy for differentiating colorectal neoplastic polyps in a health screening center

Emura

Saito

Taniguchi

et al. 2007

J of Gastro and Hepatol

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Section: Discussionmentioning

confidence: 99%

Further validation of magnifying chromocolonoscopy for differentiating colorectal neoplastic polyps in a health screening center

Emura

Saito

Taniguchi

et al. 2007

J of Gastro and Hepatol

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“…1 a The initial colonoscopy revealed a round sessile polyp, about 2 cm in diameter in the sigmoid colon. b Magnifying view showed type V I pits with irregularity at the top of this lesion colonoscopic examinations have detected cancers that arise de novo in addition to superficial-type cancers [7][8][9]; however, the main route of colon cancer developmentwhether it is from an adenoma-carcinoma sequence or de novo-is not yet known.…”

Section: Discussionmentioning

confidence: 99%

Sigmoid colon carcinoma that developed from a sessile-type cancer in a short period of time

Tomiki

Ono

Ishiyama

et al. 2010

Clin J Gastroenterol

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We report a case of sigmoid colon carcinoma that developed from a sessile-type cancer in a short period of time. An 83-year-old man was found to have a round sessile polyp, about 2 cm in diameter, in the sigmoid colon. Because he had taken anticoagulants, immediate endoscopic mucosal resection and biopsy were not performed. Forty-three days later, the apical surface of the sessile polyp had become depressed and ulcerated, and we judged that an endoscopic resection was not indicated for this lesion. The histologic diagnosis of the biopsy specimens was a well-differentiated adenocarcinoma. We recommended surgical treatment; however, the patient was not in favor of surgical treatment and would not consent to surgery. Two more examinations were performed and the tumor was found to have developed into an invasive cancer with ulcerated, nodular margins involving 3/4 of the colonic lumen. At 271 days after the initial examination, the patient finally consented to surgery and a partial resection of the sigmoid colon was performed. The tumor was classified as stage I (T2N0M0). The several examinations performed from presentation within a short time span provide evidence of the morphologic changes that occur when a sessile-type cancer develops into an ulcerating invasive cancer. We hypothesize that remarkable configuration changes and development take place when a tumor becomes invasive in the muscularis propria from massive submucosal invasion. Our findings suggest that among the tumors discovered as typical ulcerating invasive type colon cancers are those that developed from protuberant tumors in a short period of time.

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“…From an extensive review of retrospective endoscopic studies, we collected just 26 case reports (27 lesions) over a period of 20 years 1,12–35 . By adding our eight cases we could analyze 35 lesions of retrospective endoscopic study.…”

Section: Discussionmentioning

confidence: 99%

Retrospective endoscopic study of developmental and configurational changes of early colorectal cancer: Eight cases and a review of the literature

Matsui

Tsuda

Iwashita

et al. 2003

Digestive Endoscopy

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Background : A retrospective endoscopic follow-up study was conducted to elucidate the development of minute or superficial-type cancers. Methods : The development of eight colorectal cancers that were followed up by endoscopy was evaluated. Results : (i) Cancer with high-grade atypia frequently developed from lesions diagnosed histologically by biopsy as adenoma; (ii) two polypoid adenomas developed into invasive cancers with non-polypoid configuration; (iii) a superficial elevated-type cancer with high-grade atypia remained a mucosal cancer for more than 1 year; (iv) a superficial depressed (SD)-type cancer that had a concomitant adenomatous component grew slowly, maintaining the same configuration for more than 2 years. Another SD-type cancer grew rapidly to an advanced cancer; and (v) a superficial elevated adenoma developed into a IIa + IIc-type submucosally invasive cancer while maintaining the size of the initial tumor. From the analysis of the literature, 35 lesions were collected, but it was impossible to speculate which specific type of tumor grew rapidly. Conclusions : From the endoscopic observations of the present study and the review of the literature, developments of superficial type cancers were diverse, sessile-type cancers with marked configurational change, and early cancers developed slowly, although the speed of their growth accelerated according to the downward invasion of the cancer.

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Superficial Depressed-Type Cancer Monitored by Colonoscopy through the Early Phase of Invasion

Cited by 7 publications

References 15 publications

Further validation of magnifying chromocolonoscopy for differentiating colorectal neoplastic polyps in a health screening center

Further validation of magnifying chromocolonoscopy for differentiating colorectal neoplastic polyps in a health screening center

Sigmoid colon carcinoma that developed from a sessile-type cancer in a short period of time

Retrospective endoscopic study of developmental and configurational changes of early colorectal cancer: Eight cases and a review of the literature

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