Superficial Hemangiomas: Associations and Management

Abstract

The vast majority of hemangiomas, the most common skin tumor of infancy, are small lesions, easily recognized by their clinical features, and left to involute spontaneously. Hemangiomas also grow in a number of visceral locations, although rarely. In addition, associated malformations are reported. We analyzed 175 cases of severe superficial hemangiomas that represented approximately 10% of all hemangiomas evaluated from 1980 to 1995. In this particular group of severe hemangiomas, with marked female preponderance (6.6:1), symptomatic visceral hemangiomas were present in 20 of 175 patients (11.4%) and associated malformations were present in 12 patients (6.9%), with both present in 4 patients. We describe these associations and discuss which hemangiomas required active treatment and which therapeutic modalities can be used. Progress has been made in the management of problem hemangiomas.

Hypoxia-Induced Mediators of Stem/Progenitor Cell Trafficking Are Increased in Children With Hemangioma

“…These lesions are found more frequently in the head and neck regions with a 3-fold higher incidence in females. [3][4][5] Infantile hemangioma is the most common tumor of infancy, yet few effective treatments are available due to a fundamental lack of knowledge in hemangioma biology. 6 The majority of hemangioma research has focused on the mechanisms of angiogenesis as underlying the new blood vessel growth.…”

Evaluation of hemangioma management in Erbil city

“…The ratio of female to male in our group of patients was 2:1, which was similar to the ratio generally reported in the literature of 2-5:1. 10,12,13 The management of hemangiomas has been a subject of intense controversy for many decades. They are remarkably heterogeneous regarding size, location, and rate of growth and involution.…”

Evidence-Based Medicine in the Treatment of Infantile Hemangiomas

“…5,6 IHs occur between 3 and 6 times more frequently in girls than boys; are seen more often in whites, premature infants, and twins; and tend to afflict offspring of mothers of higher maternal age. 5,7,8 Approximately 60% of these occur in the head and neck region, 25% on the trunk and 15% on the extremities. 9 At birth, most IHs are absent or have a small premonitory mark, such as a pale macule.…”