Superficial vaginal myofibroblastoma with mushroom-like appearance: A case report with colposcopic findings and literature review

Abstract

Superficial myofibroblastoma (SMF) of the lower female genital tract is a relatively rare benign mesenchymal tumor. The diagnosis is usually challenging as it shares several similar clinicopathological features with other tumors. Herein, we present a case of a 71-year-old Chinese female patient with postmenopausal vaginal bleeding. Colposcopy imaging revealed a well-circumscribed mass in the vagina with a wide pedicle, resembling a mushroom. The patient underwent surgery, and the tumor was histologically diagnosed as SMF. To the best of our knowledge, this is the first report of colposcopic imaging of a superficial vaginal myofibroblastoma. In this case study, we review the clinicopathological features of SMF of the lower female genital tract reported in the literature to improve the understanding of the disease.

Case report: Superficial cervicovaginal myofibroblastoma of the cervix with endometrial carcinoma

“…Laskin et al reported 14 cases of subepithelial mesenchymal tumors in the female genital tract ( 1 ). Superficial cervical vaginal myofibroblastoma is rare with only 57 reported cases, involving the female genital tract ( 2 ). This was the first report of concomitant SCVM and endometrioid carcinoma in a patient with a history of breast carcinoma.…”

Vulval superficial myofibroblastoma with lymphocytic and eosinophilic infiltrate

“…Superficial myofibroblastomas are rare benign tumours of the female lower genital tract, with most cases reported in the literature occurring in the vagina 1–13…”

“…Superficial myofibroblastomas are rare benign tumours of the female lower genital tract, with most cases reported in the literature occurring in the vagina. [1][2][3][4][5][6][7][8][9][10][11][12][13] Here, we report a vulval superficial myofibroblastoma with an unusual finding of an inflammatory infiltrate consisting of lymphocytes and eosinophils at the rim and also within the tumour. While mast cells and lymphoid aggregates have been reported in superficial myofibroblastoma, we can find no existing report of an infiltrate of lymphocytes with rimming the tumour.…”

“…Most commonly, they are seen in the vagina but also occur in the cervix and vulva. Less than 60 cases have been reported 2–12. No more than seven cases relate specifically to the vulva 2 3 8 10 11.…”

“…Less than 60 cases have been reported. [2][3][4][5][6][7][8][9][10][11][12] No more than seven cases relate specifically to the vulva. 2 3 8 10 11 There is a wide age range from 23 to 80 years.…”