Breast is one important organ of women that not only has functional importance of lactation, but also defines the femininity of a woman. Any lass of breast either partial or total may cause psychosocial impact on women’s life. Thus, in case of loss due to various reasons, plastic surgeons involved in oncosurgery team should offer reconstruction to restore breast volume, size, and self-esteem of patients. The chapter aims to describe the various deformities of the breast following cancer, trauma, burn, and reconstructive options in terms of flaps. The various flaps described for breast reconstruction are LD flap, TRAM flap, DIEP flap, and expander implant techniques. The readers will be able to execute the planning for breast reconstruction knowing the indications and contraindications of using a particular flap, surgical techniques of flap elevations, and post-operative care and management.