Superior mesenteric artery thrombosis in a patient with COVID-19 pneumonia and <i>Clostridium Difficle</i>

Maniar, Yesha; Hashmi, Hassan; Silverstein, Jeffrey H.; Chung, Christine H.; Kella, Venkata; Goparaju, Anirudha

doi:10.1093/jscr/rjac146

Cited by 3 publications

(3 citation statements)

References 9 publications

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“…The jejunum, the ileum, and the colon are supplied mostly by the SMA [ 3 ]. SMA blockage from embolism causes 70% of instances of AMI, while thrombosis causes 30% of cases [ 1 ]. Abdominal emergencies like AMI are uncommon and typically necessitate broad intestine resection, have a high fatality rate, and, in individuals who survive, cause short-bowel syndrome [ 3 ].…”

Section: Discussionmentioning

confidence: 99%

“…The interaction of hypercoagulability, endothelial dysfunction, hypoxia, and immobility may account for AMI in COVID-19, even though the precise pathophysiology is uncertain [ 1 ]. COVID-19 is connected to two diseases: (1) endotheliitis brought on by diffuse endothelial damage and infiltration of inflammatory cells and (2) a systemic hypercoagulable state brought on by hyperinflammation and hypercytokinemia.…”

Section: Discussionmentioning

confidence: 99%

“…COVID-19 is a unique respiratory virus that mostly spreads through respiratory droplets, which led to a pandemic that affected the whole world. Primary occurrences took place in Wuhan, China, more than four years ago, when patients originally came with pneumonia of unclear origin and respiratory symptoms [ 1 ].…”

Section: Introductionmentioning

confidence: 99%

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Superior Mesenteric Artery Thrombosis in COVID-19-Positive Patients: A Rare Coincidence

Parekh,

Athavale,

Kelshikar

2024

Cureus

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Since the start of the SARS-CoV-2 pandemic, which is otherwise known as the worldwide coronavirus disease, 2019, has had a well-established pro-thrombotic character. Patients often first exhibit respiratory symptoms, and those whose severity increases eventually develop acute hypoxic respiratory failure. The systemic hypercoagulable condition and arterial/venous thrombosis related to COVID-19 have a poor prognosis. Even though superior mesenteric artery (SMA) thrombosis and acute mesenteric ischemia (AMI) are uncommon, they frequently coexist with fatal gastrointestinal (GI) pathologies that necessitate prompt diagnosis and treatment by the doctor. This calls for more research into the effects of anticoagulation therapy in COVID-19-positive patients. The main treatment aims for this condition are early detection, surgical or intravascular re-establishment of blood supply to the ischemic bowel, and surgical resection. The study aimed to see the outcome after surgical intervention in patients with SMA thrombosis post-COVID-19 infection. This study was from March 2021 to January 2022, with a sample size of 5 patients with SMA thrombosis, which was confirmed on contrast-enhanced computed tomography (CECT) abdomen and pelvis with angiography. The patients underwent exploratory laparotomy. Bowel resection and anastomosis were performed in three individuals; bowel resection and stoma placement were performed in two patients. Doctors have significant clinical challenges as a result of the thromboembolic manifestations of the unexpected and deadly nature of the virus, such as AMI. The high morbidity and mortality associated with AMI calls for further study on prophylactic anticoagulation therapy in COVID-19-positive individuals.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Superior Mesenteric Artery Thrombosis in COVID-19-Positive Patients: A Rare Coincidence

Parekh,

Athavale,

Kelshikar

2024

Cureus

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Upper mesenteric artery thrombosis as a complication of Clostridium difficile infection

Mastroianni¹,

Vangeli²,

Mauro³

et al. 2023

The American Journal of Emergency Medicine

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SARS-COV-2-related superior mesenteric artery thrombosis resulting in pneumatosis intestinalis complicated by pneumatosis portalis in a young male: a case report

Aryal

Bhattarai

Sharma

2023

Annals of Medicine &Amp; Surgery

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The novel coronavirus disease-2019 (COVID-19) caused by the severe acute respiratory syndrome coronavirus 2 is a highly contagious disease that has rapidly spread throughout the world. In addition to respiratory complications, the virus has also been linked to damage other organ systems as well as coagulopathy. The features and clinical spectrum of COVID-19 are continually emerging, with growing evidence of its connection to thrombosis in various systems. In this case report, the authors present a case of COVID-19 infection in a young male patient who had superior mesenteric artery thrombosis with pneumatosis intestinalis complicated by hepatic portal venous gas.

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Superior mesenteric artery thrombosis in a patient with COVID-19 pneumonia and Clostridium Difficle

Cited by 3 publications

References 9 publications

Superior Mesenteric Artery Thrombosis in COVID-19-Positive Patients: A Rare Coincidence

Superior Mesenteric Artery Thrombosis in COVID-19-Positive Patients: A Rare Coincidence

Upper mesenteric artery thrombosis as a complication of Clostridium difficile infection

SARS-COV-2-related superior mesenteric artery thrombosis resulting in pneumatosis intestinalis complicated by pneumatosis portalis in a young male: a case report

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