Superior Rectal Artery Embolization with Tris-Acryl Gelatin Microspheres: A Randomized Comparison of Particle Size

Küçükay, Murat Bülent; Küçükay, Fahrettin

doi:10.1016/j.jvir.2021.02.011

Cited by 17 publications

(20 citation statements)

References 23 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Moreover, using particles less than 900 µm showed minor complication: 45% rate of superficial ulcerations (<5 mm) at the embolized area, 7% of small recto-sigmoid junction ulcerations, and 2% of small fibrotic scar tissue in the treated zone. The only comparative study between different sizes of TAGp showed similar results in terms of HD control in all particle dimensions groups [25].…”

Section: Hemorrhoid's Embolization Outcome and Resultsmentioning

confidence: 79%

“…The use of particles also solves the issue of the recanalization of coils. Four papers reported the use of tris-acryl gelatin particles (TAGp); no comment on the rationale to TAGp use versus PVA particles was done by the authors [22,[24][25][26]. Nowadays, no data on the caliber of the anastomosis are available to understand the right particle size.…”

Section: Embolization Agentsmentioning

confidence: 99%

“…Nowadays, no data on the caliber of the anastomosis are available to understand the right particle size. Küçükay et al performed a randomized trial to understand the best tris-acryl gelatin particles size (500-700, 700-900, and 900-1200 µm) [25]. The earliest significant bleeding control was achieved with 500-700 µm particles, and the best bleeding control and lower complication rate was achieved with 900-1200 µm particles at 12 months [24,25].…”

Section: Embolization Agentsmentioning

confidence: 99%

“…Küçükay et al performed a randomized trial to understand the best tris-acryl gelatin particles size (500-700, 700-900, and 900-1200 µm) [25]. The earliest significant bleeding control was achieved with 500-700 µm particles, and the best bleeding control and lower complication rate was achieved with 900-1200 µm particles at 12 months [24,25]. A recent retrospective analysis to compare safety and clinical outcomes of embolization using particles and coils versus coils only reported a technical success of 100% and no major complications in both groups.…”

Section: Embolization Agentsmentioning

confidence: 99%

See 3 more Smart Citations

Hemorrhoids Embolization: State of the Art and Future Directions

Rebonato

Maiettini

Patriti

et al. 2021

JCM

View full text Add to dashboard Cite

Hemorrhoidal disease is a frustrating problem that has a relevant impact on patients’ psychological, social, and physical well-being. Recently, endovascular embolization of hemorrhoids has emerged as a promising mini-invasive solution with respect to surgical treatment. The purpose of this article is to review the indications, technical aspects, clinical outcomes, and future prospective of endovascular embolization of symptomatic hemorrhoid patients.

show abstract

Section: Hemorrhoid's Embolization Outcome and Resultsmentioning

confidence: 79%

Section: Embolization Agentsmentioning

confidence: 99%

Section: Embolization Agentsmentioning

confidence: 99%

Section: Embolization Agentsmentioning

confidence: 99%

See 2 more Smart Citations

Hemorrhoids Embolization: State of the Art and Future Directions

Rebonato

Maiettini

Patriti

et al. 2021

JCM

View full text Add to dashboard Cite

show abstract

“…In most of the published series, technical success rates of 90–100% have been reported, while clinical success rates range from 63% to 97% [ 11 , 12 , 16 , 17 , 18 , 19 , 23 , 24 , 25 , 26 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , 35 ]. However, it is difficult to compare the results from the different series as there is no single and homogeneous criterion and standard that defines clinical success [ 7 ].…”

Section: Discussionmentioning

confidence: 99%

Safety and Effectiveness of a New Electrical Detachable Microcoil for Embolization of Hemorrhoidal Disease, November 2020–December 2021: Results of a Prospective Study

Gregorio

Bernal

Ciampi-Dopazo

et al. 2022

JCM

View full text Add to dashboard Cite

Purpose: The purpose of this study was to prospectively evaluate the efficacy and safety of a new, bare platinum, detachable microcoil as a metallic embolization agent in the treatment of hemorrhoidal disease. Material and Methods: This prospective single-center study evaluated a new, bare platinum, electrical, detachable microcoil (Prestige plus coil (Balt Montmorency France)) for use in vascular embolization in patients with hemorrhoidal disease. Between January 2020 and January 2021, 24 embolization procedures were performed in 21 patients (12 males, 9 females; mean age 44.3 ± 7.3). The inclusion criteria were: (a) participants with grade I, II and III hemorrhoidal disease on the Goligher classification; (b) patients older than 18 years of age with a score of greater than 4 on the French bleeding score (FBS) scale; (c) patients with scores greater than 2 on the scale of discomfort proposed by Tradi and Farfallah. (d) patients who underwent treatment that included the use of the new novel coil (Prestige plus coil (Balt)) as an embolic material. The exclusion criteria were participants who failed to provide informed consent and participants diagnosed with rectal bleeding due to other causes (cancer, fissures or others). Participants with severe renal insufficiency, non-correctable coagulation abnormalities and adverse reactions to the contrast medium not correctable with medication were also excluded. The symptoms, technical aspects, the transarterial approach, clinical and technical success complications and short-term outcomes were assessed. Results: Technical success was obtained in 100% of the cases. Seventeen (80.9%) patients experienced improvements in their hemorrhoidal disease. The VAS and QL scores improved by 4 and 1.5 points (81.2% and 87.5%), respectively, after embolization (pV: 0001). Three (14.2%) patients underwent a second embolization due to rebleeding. One patient (4.7%) underwent surgery. No major complications were observed. Three patients had minor complications. The assessment of subjective post-treatment symptoms and QL surveys showed significant differences from the baseline survey. Likewise, the measurement of the degree of satisfaction using a telephone survey at 12 months revealed a high degree of patient satisfaction over 10 points (mean 8.3 ± 1.1). Conclusions: The present study demonstrates that the use of the new, platinum, detachable, electrical microcoil is safe and well-tolerated in the treatment of hemorrhoidal disease. Key points: Catheter-directed hemorrhoidal dearterialization (CDHD) is the procedure of embolization with embolic agents for the treatment of internal hemorrhoids. CDHD is a simple and safe procedure that is accepted by patients and preserves the anal sphincter; it presents few complications when metal devices or microspheres are used as embolic agents. As the recommended embolization agent in treatments, the Prestige electrical, detachable coil is a safe, easy-to-use and effective arterial embolic device.

show abstract

Recent Progress in Advanced Hydrogel‐Based Embolic Agents: From Rational Design Strategies to Improved Endovascular Embolization

Ullah

et al. 2023

Adv Healthcare Materials

View full text Add to dashboard Cite

Transcatheter arterial embolization, a minimally invasive treatment to deliberately occlude the blood vessels, has become a safe and effective procedure for the management of vascular diseases and benign/malignant tumors. Particularly, hydrogel‐based embolic agents have garnered much attention because of their potential to address some of the limitations of clinically used embolic agents and can be rationally designed to impart more favorable characteristics or functions. In this review, the recent progress toward the development of polymer‐based hydrogels for effective endovascular embolization, including the in situ gelling hydrogels mediated by physically or chemically crosslinking, imageable hydrogels for intraprocedural and postprocedural feedback, use of hydrogels as the drug depot for local delivery of therapeutic drugs, hemostatic hydrogels inducing extrinsic or intrinsic coagulation of blood, stimuli‐responsive shape memory hydrogels as the smart embolization devices, and hydrogels incorporating external‐stimuli functional materials for multidisciplinary therapy, is systemically summarized. Moreover, the potential considerations of hydrogel‐based embolic agents confronted in therapeutic embolization are pointed out. Finally, the perspectives for the development of more effective embolic hydrogels are also highlighted.

show abstract

Superior Rectal Artery Embolization with Tris-Acryl Gelatin Microspheres: A Randomized Comparison of Particle Size

Cited by 17 publications

References 23 publications

Hemorrhoids Embolization: State of the Art and Future Directions

Hemorrhoids Embolization: State of the Art and Future Directions

Safety and Effectiveness of a New Electrical Detachable Microcoil for Embolization of Hemorrhoidal Disease, November 2020–December 2021: Results of a Prospective Study

Recent Progress in Advanced Hydrogel‐Based Embolic Agents: From Rational Design Strategies to Improved Endovascular Embolization

Contact Info

Product

Resources

About