Superior thyroid artery mean peak systolic velocity for the diagnosis of thyrotoxicosis in Japanese patients

Uchida, Toyoyoshi; Takeno, Kageumi; Goto, Masahiro; Kanno, Rei; Kubo, Sachiko; Takahashi, Satoshi; Azuma, Kousuke; Sakai, Ken; Fujitani, Yoshio; Hirose, Takahisa; Kawamori, Ryuzo; Watada, Hirotaka

doi:10.1507/endocrj.k09e-263

Cited by 31 publications

(27 citation statements)

References 14 publications

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“…A maximum blood flow rate of the superior thyroid artery on ultrasonic pulse Doppler that exceeds 45 cm/sec supports a diagnosis of Graves’ disease (40). Additionally, a ratio of 0.5 or more between blood flow pixels/total pixels as measured by a semi-quantitative method is a diagnostic indicator for Graves’ disease (41).…”

Section: Diagnosis Of Graves’ Diseasementioning

confidence: 87%

Guidelines for the treatment of childhood-onset Graves’ disease in Japan, 2016

Minamitani¹,

Sato

Ohye

et al. 2017

Clin Pediatr Endocrinol

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Abstract.Purpose behind developing these guidelines: Over one decade ago, the “Guidelines for the Treatment of Graves’ Disease with Antithyroid Drug, 2006” (Japan Thyroid Association (JTA)) were published as the standard drug therapy protocol for Graves’ disease. The “Guidelines for the Treatment of Childhood-Onset Graves’ Disease with Antithyroid Drug in Japan, 2008” were published to provide guidance on the treatment of pediatric patients. Based on new evidence, a revised version of the “Guidelines for the Treatment of Graves’ Disease with Antithyroid Drug, 2006” (JTA) was published in 2011, combined with the “Handbook of Radioiodine Therapy for Graves’ Disease 2007” (JTA). Subsequently, newer findings on pediatric Graves’ disease have been reported. Propylthiouracil (PTU)-induced serious hepatopathy is an important problem in pediatric patients. The American Thyroid Association’s guidelines suggest that, in principle, physicians must not administer PTU to children. On the other hand, the “Guidelines for the Treatment of Graves’ Disease with Antithyroid Drug, 2011” (JTA) state that radioiodine therapy is no longer considered a “fundamental contraindication” in children. Therefore, the “Guidelines for the Treatment of Childhood-Onset Graves’ Disease with Antithyroid Drug in Japan, 2008” required revision.

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Section: Diagnosis Of Graves’ Diseasementioning

confidence: 87%

Guidelines for the treatment of childhood-onset Graves’ disease in Japan, 2016

Minamitani¹,

Sato

Ohye

et al. 2017

Clin Pediatr Endocrinol

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“…These data suggest that measurement of TRAb or

^{99 m} {TcO}_{4}^{-}

uptake is essential for accurate diagnosis of thyrotoxicosis with hypovascularity. In clinical settings, results of TRAb testing are not always available; thus, the superior thyroid artery PSV is helpful for discriminating patients with thyrotoxicosis 6 , 7 . In this regard, our data showed that the superior thyroid artery PSV can be moderately useful for discriminating patients with Graves disease and pattern 0 from those with painless thyroiditis and pattern 0.…”

Section: Discussionmentioning

confidence: 69%

“…Power Doppler sonographic findings, mean superior thyroid artery PSV, and thyroid volume were measured in all patients by 2 experts using a 12.0‐MHz linear transducer (LOGIQ P6; GE Healthcare, Tokyo, Japan) as described previously 6 . All assessments of intrathyroid vascularity were performed with a standardized machine setting: pulse repetition frequency of 1.2 kHz and wall filter of 141 Hz.…”

Section: Methodsmentioning

confidence: 99%

“…Among them, 13 (92.9%) were classified as having pattern 0, 1 as having pattern I (7.1%), and none as having pattern II or III. For superior thyroid artery PSV measurement, the Doppler spectral time‐averaged mean velocity and vessel diameter were obtained with the angle between the ultrasound beam and the vessel axis kept at 60° or less, and then the blood flow in the thyroid artery was calculated automatically (formula: mean velocity × 60 seconds × π r 2 ) 6 . The thyroid volume was calculated by the ellipsoid model [(width × length × thickness × π/6) for each lobe + (width × length × thickness) for isthmus].…”

Section: Methodsmentioning

confidence: 99%

“…With regard to precise evaluation of intrathyroid vascularity, power Doppler sonography is more sensitive in detecting weak blood flow than color flow Doppler sonography, 4 , 5 thus explaining its frequent use in clinical practice. Also, an elevated mean superior thyroid artery peak systolic velocity (PSV) is known to be a typical finding in Graves disease, although adequate skill is required for accurate measurement of the superior thyroid artery PSV 3 , 6 , 7 …”

mentioning

confidence: 99%

See 2 more Smart Citations

Characteristics of Patients With Graves Disease and Intrathyroid Hypovascularity Compared to Painless Thyroiditis

Uchida

Shigihara

Takeno

et al. 2014

J of Ultrasound Medicine

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Superb Microvascular Imaging in the Evaluation of Pediatric Graves Disease and Hashimoto Thyroiditis

Bayramoğlu

Kandemirli

Sarı

et al. 2019

J of Ultrasound Medicine

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Objectives-We aimed to investigate the differences between spectral Doppler and Superb Microvascular Imaging (SMI; Canon Medical Systems, Tokyo, Japan) findings in children with Hashimoto thyroiditis (HT) and Graves disease (GD) compared to healthy control participants.Methods-The study included 34 patients with GD, 37 patients with HT, and 22 healthy volunteers. All patients with HT and 11 patients with GD were euthyroid; 23 patients with GD had symptoms of hyperthyroidism and had thyrotropin values of less than 0.5 mIU/L. Thyroid volumes, mean resistive indices, and peak systolic velocities along with vascularity indices (VIs) on Superb Microvascular Imaging were measured.

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Superior thyroid artery mean peak systolic velocity for the diagnosis of thyrotoxicosis in Japanese patients

Cited by 31 publications

References 14 publications

Guidelines for the treatment of childhood-onset Graves’ disease in Japan, 2016

Guidelines for the treatment of childhood-onset Graves’ disease in Japan, 2016

Characteristics of Patients With Graves Disease and Intrathyroid Hypovascularity Compared to Painless Thyroiditis

Superb Microvascular Imaging in the Evaluation of Pediatric Graves Disease and Hashimoto Thyroiditis

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