Superiority of the Combination of Input and Output Parameters to the Single Parameter for Lesion Size Estimation

Abstract

used to estimate RF lesion size in the clinical setting, little is known about the usefulness of combining these parameters for predicting lesion size. We recently reported that local impedance (LI), an output parameter, significantly improved lesion size estimation when combined with ablation energy (AE). 12 However, it remains unclear whether the combination of AE and conventional generator impedance improves lesion size prediction compared with their sole use. Therefore, in this study we investigated the utility of a combined parameter to predict lesion size. Methods Ex-Vivo ModelA section of the porcine left ventricular myocardium R adiofrequency (RF) catheter ablation is the standard treatment for cardiac arrhythmias, 1,2 but despite efforts at refining ablation technology, including the development of irrigated-tip and contact force (CF)-sensing ablation catheters, success rates of catheter ablation procedures for atrial and ventricular arrhythmias are suboptimal. 3 To prevent arrhythmia recurrence, creating a durable lesion of optimal size is one of the most important factors, 4 and several studies have reported that input factors such as RF power and duration show a positive correlation with lesion size. 5-7 On the other hand, impedance has been used as an output parameter to predict lesion formation because it provides information regarding the tissue reaction during RF ablation. [7][8][9][10][11] Because each input and output parameter is individually

Safety verification of a novel irrigation catheter with flexible tip of laser‐cut kerfs and contact force sensor

“…However, when high‐power ablation at 50 W is applied using TactiFlex, it can create lesions approximately 2–3 mm in depth in 10 s (500 J) and 3–5 mm in depth in 20 s (1000 J) 19,20 . For PVI, 10 s may suffice for thinner segments, while up to 20 s may be necessary for thicker segments.…”

“…However, when high-power ablation at 50 W is applied using Tac-tiFlex, it can create lesions approximately 2-3 mm in depth in 10 s (500 J) and 3-5 mm in depth in 20 s (1000 J). 19,20 For PVI, 10 s may suffice for thinner segments, while up to 20 s may be necessary for thicker segments. Clinical studies have demonstrated the efficacy and safety of applying 40−50 W for 10−20 s using TactiFlex in a clinical setting.…”