Superoxide dismutases from a blue-green alga, Plectonema boryanum.

Oxygen evolution from hydrogen peroxide in photosystem II: flash-induced catalytic activity of water-oxidizing photosystem II membranes

“…The lsO content of the hydrogen [18Ojperoxide was 81% based on the ratio of l802/,602 evolved after the addition of catalase to the mass spectrometer vessel. Mn-SOD from Serratia marcesens (Wako Pure Chemical Industries, Ltd., Japan) was used because it is not inactivated by hydrogen peroxide (Asada et al, 1975).…”

Potentiometric titrations and oxidation-reduction potentials of several iron superoxide dismutases

“…The iron-containing superoxide dismutases, which normally have two identical 20 000-dalton subunits with one iron per subunit (a four-subunit protein has been reported; Kusonose et al, 1976), exhibit unique spectral and annulation properties (Slykhouse & Fee, 1976;Asada et al, 1975;Fee et al, 1981a).…”

“…The EPR spectrum (gav = 4.3) is characteristically rhombic and has been shown to possess unusual magnetic properties (Emptage, 1981). Azide and fluoride act as inhibitors (Misra & Fridovich, 1978;Fee et al, 1981a) of the dismutase activity while cyanide is not an inhibitor nor does it bind to the Fe(III) (Asada et al, 1975; Slykhouse & Fee, 1976). Hydrogen peroxide rapidly destroys the catalytic activity, and this process has been used to dis-0006-2960/83/0422-0624S01.50/0 © 1983 American Chemical Society tinguish the iron dismutases from the manganese dismutases in crude cell extracts (Okada et al, 1979).…”

Comparative Genomic and Physiological Analyses of a Superoxide Dismutase Mimetic (SODm-123) for Its Ability to Respond to Oxidative Stress in Tomato Plants

“…Common SODm includes metal complexes (metallocorroles, metalloporphyrins, Mn­(III) salen derivatives, and Mn­(II) cyclic polyamines) and non-metal based compounds (fullerenes, nitroxides, and nitrones). − Generally, the metal complexes have been the most preferable SODm because they can easily accept/donate electrons and reduce O 2 –• to harmless compounds. In addition, among the metal cofactors residing at the active site of SOD, Mn is more favorable because (1) Mn has an unrivaled repertoire of redox capacities; (2) Mn is a more favorable O 2 –• remover than Fe, as it precludes the release of “free” iron, which may lead to Fenton-based toxicity; and (3) unlike Cu/Zn-SOD, Mn-SOD does not exhibit product inhibition by H 2 O 2 . − Thus, a variety of catalytic systems in which manganese is used as the metal cofactor in the active sites has been designed, , including Mn-Schiff base complexes, Mn-amine and diamine complexes, Mn­(II) azamacrocyclic complexes, manganese porphyrin (MnP) corroles, and some other Mn complexes of acyclic ligands. ,− …”