2000
DOI: 10.1007/bf03045025
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Supine cephalometric analyses of an adjustable oral appliance used in the treatment of obstructive sleep apnea

Abstract: OBJECTIVE: To investigate the effects of the Klearway(TM) appliance on the upper airway in patients with obstructive sleep apnea (OSA) in the supine position. METHODS: Sixteen subjects (12 males and 4 females) were recruited on the basis of baseline polysomnography with a documented Apnea and Hypopnea Index (AHI) >15 per hour. A second overnight sleep study was performed for each subject with the appliance in place. Baseline supine cephalometry was performed for each subject before the initial insertion of the… Show more

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Cited by 44 publications
(19 citation statements)
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“…No significant difference in the amount of mandibular advancement was found in our study between the responders and non-responders, which corroborates the results of Mostafiz et al 23 An increase in the elasticity of the tongue's soft tissue might limit the mechanical transmission of the mandibular advancement force to the base of the tongue. 39,42 In agreement with the findings by Liu et al 10 and Otsuka et al, 39 we also found a reduction in the lower airway space in the responders. Individuals with a narrowing of the upper airways exhibited a greater tendency for collapse; thus, we may postulate that a volumetric increase in this area induced by an MRA, even in an upper location, might contribute to a reduction in the airway collapsibility, thereby promoting treatment success.…”
Section: 38supporting
confidence: 82%
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“…No significant difference in the amount of mandibular advancement was found in our study between the responders and non-responders, which corroborates the results of Mostafiz et al 23 An increase in the elasticity of the tongue's soft tissue might limit the mechanical transmission of the mandibular advancement force to the base of the tongue. 39,42 In agreement with the findings by Liu et al 10 and Otsuka et al, 39 we also found a reduction in the lower airway space in the responders. Individuals with a narrowing of the upper airways exhibited a greater tendency for collapse; thus, we may postulate that a volumetric increase in this area induced by an MRA, even in an upper location, might contribute to a reduction in the airway collapsibility, thereby promoting treatment success.…”
Section: 38supporting
confidence: 82%
“…9 However, the inability to predict which patients will respond well to the treatment limits the clinical use of an MRA. 10 The construction of a custom-made device for each patient and a titration period for the mandible to adapt demands time and money.…”
Section: Introductionmentioning
confidence: 99%
“…of snores/min; snoring eliminated in 8/51, improved in 43/51[46]25MAASnoring less than “moderate” in 19/25 pts[47]23MAA“...20/23 patients (87%) reported subjective improvement...in snoring”[49]23TRD“Visual analog scores of snoring...were also reduced significantly” in 6/23 (23%) subjects[53]23MAA“...loud snore duration was reduced from a median of 27.1 min to 11.4 min”[54]44MAA“Snoring was satisfactorily reduced in” 37/44 patients (84%)[57]15MAA19320Median snores/h given; snoring loudness and time spent snoring also improved[102]132MAA“Snoring was reported...to be satisfactorily controlled in 107 (81%)...[58]14MAA6/14—no snoring; 8/14—mild snoring[59]41MAA0.70.5No. of snores/h of sleep at baseline and 12 months follow-up (NS)[60]75MAA“Dramatic reduction in the attributes of snoring was achieved”[66]112MAA76/112 (68%) snoring either eliminated or acceptable[68]24MAA5033No of snores/h sleep; results for Herbst appliance; 19/20 disturbed by snoring at baseline, vs 9/20 with appliance[21]10TRD113Percent of time spent in loud snoring[69]39MAA“Time with snoring dropped significantly from 16.3% to 6.6%”[71]22MAASnoring eliminated in 13/22, significantly reduced in 5/22; success rate = 18/22 (82%)[104]53MAAQuestionnaire survey; 27...…”
Section: Oral Appliances For the Treatment Of Snoringmentioning
confidence: 99%
“…This reduction can be achieved by using continuous positive airway pressure (CPAP); however, the success of CPAP treatment is limited because patient compliance and long-term acceptance remain low. 6 Compliance is better for oral appliances such as the mandibular advancement device (MAD), but the treatment efficacy is lower for oral appliances than for CPAP. [7][8][9] Surgical therapy is another therapeutic option.…”
Section: Introductionmentioning
confidence: 99%