“…A number of antioxidants including coenzyme Q10 (Fischer, Niklowitz, Menke, & Döring, 2014), resveratrol (Regitz, Fitzenberger, Mahn, Dußling, & Wenzel, 2016) and tea polyphenols (Deusing et al, 2015) have been found to extend the lifespan of C. elegans. A recent study has shown that AST could increase the lifespan of C. elegans (Yazaki, Yoshikoshi, Oshiro, & Yanase, 2011), and our recent research also suggested that AST resulted in a lifespan extension via an Ins/IGF-1 signalling pathway during normal ageing of C. elegans (Luo, Liu, Cao, He, & Liu, 2015). In this study, the antioxidation and anti-ageing activities of different stereoisomeric AST were determined by chemicalbased (DPPH, ABTS and ORAC) assays, cellular-based (Caco-2) antioxidant assays, and organism-based (C. elegans) detection.…”