Supplementary Stabilization With Anterior Lumbar Intervertebral Fusion–A Radiologic Review

Anjarwalla, N; Morcom, Russel K; Fraser, Robert D.

doi:10.1097/01.brs.0000217692.90624.ab

Cited by 41 publications

(26 citation statements)

References 23 publications

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“…Li et al [9] reported a range between 51.9 and 88.9 % fusion in a literature review. Anjarwalla et al [21] assessed the fusion rate of one stand-alone cage ALIF versus the same ALIF cage with different techniques of posterior supplemental fixation. The fusion rate for the stand-alone cage was 51 % versus 89 % and 88 % for the two groups supplemented with pedicle screws.…”

Section: Discussionmentioning

confidence: 99%

Stand-alone ALIF with integrated intracorporeal anchoring plates in the treatment of degenerative lumbar disc disease: a prospective study on 65 cases

Allain

Delécrin²,

Beaurain³

et al. 2014

Eur Spine J

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Purpose ALIF with cages is expected to restore disc height and stabilize the spine promoting fusion, while avoiding damage attributed to rod-pedicle screw fixation. However, it may be related to an increased risk of fusion failure and subsidence. A prospective study was conducted by five investigators across three centers to confirm performance of a PEEK cage for stand-alone ALIF in the treatment of lumbar degenerative disc disease (DDD). Methods Sixty-five patients, with back ± leg pain, requiring surgery for DDD, were included. Efficacy and safety were evaluated at 6 weeks, 3, 6, and 12 months postoperatively. Fusion and subsidence were assessed through CT-images at 12-month follow-up. Disc height was measured. Clinical outcomes included back and leg pain (VAS), disability (Oswestry Disability Index), Quality of Life (Short-Form 36), and adverse events. Results The fusion and the subsidence rates were 96.3 and 2.0 %, respectively. ALIF surgery restored anterior and posterior disc height compared to baseline. There were no device-related serious adverse events, and no revision surgeries. Clinical outcomes improved significantly through 12-month follow-up. Conclusion Safety and efficacy of this stand-alone cage with integrated intracorporeal plates was confirmed through 12 months for treatment of degenerative conditions. The design of the cage and plates may contribute to the decreased subsidence rate observed.

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Section: Discussionmentioning

confidence: 99%

Stand-alone ALIF with integrated intracorporeal anchoring plates in the treatment of degenerative lumbar disc disease: a prospective study on 65 cases

Allain

Delécrin²,

Beaurain³

et al. 2014

Eur Spine J

View full text Add to dashboard Cite

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“…Tzermiadianos et al [75] postulated that from a biomechanical point of view, ALIF and additional ATB plating seemed to be a reasonable alternative to ALIF with posterior pedicle screw instrumentation to enhance ALIF cage stability. Furthermore, previous biomechanical, clinical and radiological studies have reported that ASAF devices such as the one that was investigated in the current study or similarly configured implants provide sufficient biomechanical stability [21,70,[75][76][77][78][79][80][81].…”

Section: Interbody Fusion Assessmentmentioning

confidence: 99%

Anterior stand-alone fusion revisited: a prospective clinical, X-ray and CT investigation

et al. 2014

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The current study delineates satisfactory clinical results following ASAF at the lumbosacral junction. Patient safety was demonstrated with acceptable complication and low reoperation rates. Radiological data demonstrated a significant reconstruction of lordosis at the lumbosacral junction. Solid interbody fusion was achieved in 97.3 % of all cases in a highly selected cohort with optimal predisposition for fusion. ASAF may serve to avoid a variety of negative side effects for a considerable number of patients which, otherwise, would have been candidates for posterior instrumented fusion techniques.

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“…In the orthopaedic implant field, several reports have found fibrous capsules around implants of metallic [18, 19] or polymeric nature [20-22]. This type of failure is commonly attributed to toxic wear debris phagocytosed by macrophages and other cells of the surrounding tissue [23-25].…”

Section: Introductionmentioning

confidence: 99%

Implant osseointegration and the role of microroughness and nanostructures: Lessons for spine implants

et al. 2014

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The use of spinal implants for spine fusion has been steadily increasing to avoid the risks of complications and donor site morbidity involved when using autologous bone. A variety of fusion cages are clinically available, with different shapes and chemical compositions. However, detailed information about their surface properties and the effects of such properties on osteogenesis is lacking in the literature. Here we evaluate the role of surface properties for spinal implant applications, covering some of the key biological processes that occur around an implant and focusing on the role of surface properties, specifically surface structure, on osseointegration, drawing examples from other implantology fields when required. Our findings revealed that surface properties such as micro-roughness and nanostructures can directly affect early cell behavior and long-term osseointegration. Micro-roughness has been well established in the literature to have a beneficial effect on osseointegration of implants. In the case of the role of nanostructures, the number of reports is increasing and most studies reveal a positive effect from the nanostructures alone and a synergistic effect when combined with micro-rough surfaces. Still, long-term clinical results are necessary to establish the full implications of surface nanomodifications.

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Supplementary Stabilization With Anterior Lumbar Intervertebral Fusion–A Radiologic Review

Abstract: The addition of pedicle screw fixation at ALIF produces a significant increase in the rate of interbody fusion.

Cited by 41 publications

References 23 publications

Stand-alone ALIF with integrated intracorporeal anchoring plates in the treatment of degenerative lumbar disc disease: a prospective study on 65 cases

Stand-alone ALIF with integrated intracorporeal anchoring plates in the treatment of degenerative lumbar disc disease: a prospective study on 65 cases

Anterior stand-alone fusion revisited: a prospective clinical, X-ray and CT investigation

Implant osseointegration and the role of microroughness and nanostructures: Lessons for spine implants

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