Supplementation of a combination of herbs improves immunity, uterine cleansing and facilitate early resumption of ovarian cyclicity: A study on post-partum dairy buffaloes

Japheth, K. Puhle; Kumaresan, A.; Patbandha, T.K.; Baithalu, Rubina Kumari; Selvan, A. Sakthivel; Nag, Pranab Kumar; Manimaran, A.; Oberoi, P. S.

doi:10.1016/j.jep.2021.113931

Cited by 9 publications

(7 citation statements)

References 37 publications

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“…Dietary curcumin promoted ovarian follicullogenesis and ovulation in the fish Pseudotropheus socolofi 23 . The plant additive containing curcumin promoted ovarian follicle development in the buffalo as well 12 . On the contrary, Destici Isgoren et al 24 did not observe an effect of the curcuma extract on rat ovarian follicle development.…”

Section: Effect On Female Reproductive Processesmentioning

confidence: 99%

“…Furthermore, evidence suggests its applicability for the prevention, mitigation, and maybe even treatment of some age-dependent reproductive disorders including late sexual maturation 19 , 20 , reproductive aging, ovarian insufficiency and failure 5 , 20 , 21 , 22 , 24 , 36 , 37 , complications during pregnancy 15 , and a prolonged postpartum period 12 . Moreover, its potential to prevent, mitigate, and treat signs of ovarian cancer 8 , 11 , 13 , 17 , 27 , 28 , 29 , 30 , 31 , 32 , 33 , 34 , polycystic ovarian syndrome 35 , 43 , 44 , and adverse effects of immunological shock 36 , hypoxia 46 , ionizing irradiation 45 , ischemia 47 , oxidative stress 44 , 48 , mykotoxins 48 , and arsenic 10 on ovarian functions suggests the large therapeutic potential of curcumin and its molecules.…”

Section: Application In Reproductive Biology and Medicinementioning

confidence: 99%

“…For example, curcumin can suppress inflammatory processes through the downregulation of intracellular promoters of inflammation such as Nrf2, NF-κB, STAT3, reactive oxygen species, and COX-2 (see [2] for review). On the other hand, curcumin can boost the functions of immunocompetent cells, the production of inflammatory cytokines, and reparative processes [11,12]. Furthermore, curcumin can suppress cancerogenesis [10,13] and other illnesses [14] targeting microRNAs and long non-coding RNAs.…”

Section: Mechanisms Of Actionmentioning

confidence: 99%

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The Influence of Turmeric and Curcumin on Female Reproductive Processes

Sirotkin

2021

Planta Med

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The present review summarizes the available knowledge concerning the action of curcumin, the best-known polyphenol among the rhizomes of Curcumas, on female reproductive processes and their dysfunctions. Curcumin affects a number of physiological processes, including female reproduction (puberty, reproductive aging, ovarian follicullogenesis and oogenesis, and fecundity). Curcumin can affect these processes via changes in the release and reception of pituitary and ovarian hormones, growth factors and cytokines. Furthermore, it can influence the response of ovarian cells to these substances and external environmental factors. Finally, curcumin can affect oxidative processes within the ovary and numerous intracellular signalling pathways related to ovarian cell proliferation and apoptosis. These effects suggest the applicability of curcumin for stimulation of female reproductive processes in vivo and in vitro, as well as for the prevention, mitigation, and treatment of various reproductive disorders from ovarian insufficiency and infertility to polycystic ovarian syndrome and ovarian cancer.

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Section: Effect On Female Reproductive Processesmentioning

confidence: 99%

Section: Application In Reproductive Biology and Medicinementioning

confidence: 99%

Section: Mechanisms Of Actionmentioning

confidence: 99%

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The Influence of Turmeric and Curcumin on Female Reproductive Processes

Sirotkin

2021

Planta Med

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“…Thus, the identification of genes and the variants associated with these traits may support selective breeding for genetic improvement. Improved immunity is equally significant to propagate uterine cleansing to facilitate an early resumption of ovarian cyclicity (8,9). Feed conversion efficiency (FCE) is defined as a dry matter intake (DMI) per unit body weight (g/day) gain determined as residual feed intake (RFI).…”

Section: Introductionmentioning

confidence: 99%

Comparative expression analysis of water buffalo (Bubalus bubalis) to identify genes associated with economically important traits

et al. 2023

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The milk, meat, skins, and draft power of domestic water buffalo (Bubalus bubalis) provide substantial contributions to the global agricultural economy. The world's water buffalo population is primarily found in Asia, and the buffalo supports more people per capita than any other livestock species. For evaluating the workflow, output rate, and completeness of transcriptome assemblies within and between reference-free (RF) de novo transcriptome and reference-based (RB) datasets, abundant bioinformatics studies have been carried out to date. However, comprehensive documentation of the degree of consistency and variability of the data produced by comparing gene expression levels using these two separate techniques is lacking. In the present study, we assessed the variations in the number of differentially expressed genes (DEGs) attained with RF and RB approaches. In light of this, we conducted a study to identify, annotate, and analyze the genes associated with four economically important traits of buffalo, viz., milk volume, age at first calving, post-partum cyclicity, and feed conversion efficiency. A total of 14,201 and 279 DEGs were identified in RF and RB assemblies. Gene ontology (GO) terms associated with the identified genes were allocated to traits under study. Identified genes improve the knowledge of the underlying mechanism of trait expression in water buffalo which may support improved breeding plans for higher productivity. The empirical findings of this study using RNA-seq data-based assembly may improve the understanding of genetic diversity in relation to buffalo productivity and provide important contributions to answer biological issues regarding the transcriptome of non-model organisms.

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“…Polyherbal formulations have more potential and advantages over single herbal formulations because of the synergistic effects and several biological functions of their contents [11]. A recent study reported that the treatment of postpartum dairy buffaloes with herbal supplementations enhanced the resumption of ovarian cyclicity [12]. Several herbs are used as natural sources of minerals, vitamins, and antioxidants.…”

Section: Introductionmentioning

confidence: 99%

Impact of polyherbal formulation oral administration on the estrus response, luteal activity, and oxidative stress in postpartum dairy cows with ovarian subfunction

et al. 2022

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Background and Aim: The reproductive performance of dairy cows is of a high economic value to maintain efficient and sustainable productivity. Postpartum anestrus is one of the major infertility problems that cause limitation of dairy cow reproductive performance and productivity. The previous studies have reported using a polyherbal formulation for different purposes, including reproductive performance. This study was conducted to examine the efficacy of polyherbal formulation administration on the reproductive performance of cows and to establish the oral administration of polyherbal formulations as a safe, effective, and economic treatment for dairy cows with postpartum anestrus due to nutritional disorders, negative energy balance, high milk production, and/or heat stress. Materials and Methods: A total of 14 dairy cows with postpartum anestrus were randomly divided into two groups, which were subjected to oral administration of distilled water that served as the control (Ctrl; n=5) or polyherbal treatment (polyherbal treated; n=9) for two shots of treatment (each for 3 successive days) with a 10-day interval. Blood sampling and ultrasonography were performed before treatment and after the first and second shots of treatment. Progesterone (P4) assay was also performed. Results: The estrus induction rate was 66.7% after the first shot of treatment in the polyherbal-treated group, which increased significantly to 88.9% after the second shot of treatment, compared with the Ctrl group (20%). The estrus response was confirmed by ultrasonography and P4 hormone assay, wherein the polyherbal treatment significantly increased the P4 concentration in the polyherbal-treated group after the second shot of treatment compared to that before treatment and in the Ctrl group at all time points. On pregnancy diagnosis, the treated dairy cows showed conception rates of 66.7% and 20.0% in the polyherbal-treated and Ctrl groups, respectively. In contrast, the concentration of malondialdehyde, an oxidative stress marker, and the total antioxidant capacity remained unchanged between both groups before and after treatment. Conclusion: The polyherbal formulation containing tubers of C. rotundus, M. pterygosperma, rhizome of Z. officinale, and A. cepa has the potential to induce estrus response and luteal activity in dairy cows and is a possible treatment for ovarian inactivity in dairy farms.

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Supplementation of a combination of herbs improves immunity, uterine cleansing and facilitate early resumption of ovarian cyclicity: A study on post-partum dairy buffaloes

Cited by 9 publications

References 37 publications

The Influence of Turmeric and Curcumin on Female Reproductive Processes

The Influence of Turmeric and Curcumin on Female Reproductive Processes

Comparative expression analysis of water buffalo (Bubalus bubalis) to identify genes associated with economically important traits

Impact of polyherbal formulation oral administration on the estrus response, luteal activity, and oxidative stress in postpartum dairy cows with ovarian subfunction

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