Firstly, the characteristics and present situations of the prefabricated construction supply chain are analyzed; inventory cost models for construction material of every phase order, one-off order, and fractionated order are built based on traditional EOQ model and construction supply chain theory. Next, the order decision is represented in binary numbers 0 and 1, in which 0 stands for "no order" and 1 for "order." The analysis uses the genetic algorithm, sets the objective function, and undergoes testing and assessing the individual fitness function, encoding, decoding, crossover, mutation, and selecting parameter. Moreover, inventory cost of construction supply chain is processed and optimized in Matlab. The research establishes a research paradigm on supply chain management of component manufacturing and materials supply. This study concludes the ordering strategy on construction material, identifies the optimal order points and order batches, and provides recommendations for further research.