Case study pedagogy is widely recognized as a powerful teaching approach in business education programs. However, its implementation in non-residential business schools poses distinct challenges. Optimizing case study pedagogy to the unique needs and circumstances of non-residential students necessitates a specific strategy. This chapter delves into various strategies essential for the effective implementation of case study pedagogy in non-residential business schools. First, an overview of the case study as a pedagogy in a business school is discussed. Further, the unique challenges are discussed. Strategies are presented to mitigate these challenges. Key strategies encompass pre-class preparation, online platform utilization, flexible class timings, active facilitation, peer learning opportunities, integration with real-world examples and faculty training. By addressing the challenges, non-residential business schools can enhance student engagement, improve learning outcomes, and create a conducive learning environment for non-residential students.